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The effectiveness and evaluation of the online 'Kanker Herstel Hulp' intervention in cancer survivors.

The project primarily aims to study short (3 and 6 months) and long term (12 months) health related effects of the 'Kanker Nazorg Wijzer' on survivors' psychosocial distress and quality of life (QoL). Furthermore, process aspects of…

The clinical relevance of axillary reverse mapping (ARM)

The objective of the study is to determine the clinical relevance of sparing the lymfdrainage of the upper extremitiy by using the ARM-procedure in patients with breast cancer. The purpose of the continuation of the feasibility study is to create a…

Treatment of Cancer in the Head and Neck:
The Role of Hyperbaric Oxygen in Reducing Swallowing Problems

Primary Study Objectives:This study tries to objectives the potential benefit of prophylactic HBOT in terms of reducing / limiting the amount of dysphagia and / or xerostomia for tumors in the head and neck, specifically originating from the…

Efficacy and Cost Efficacy of Prophylactic treatment with Antibiotics during concomitant chemoradiotherapy in patients with locally advanced head and neck cancer to prevent Aspiration Pneumonia. A randomized phase II-III study

To observe a decrease in number of definite and/or suspected pneumonia after prophylactic treatment with antibiotics during CRT in patients with LAHNC.To observe a decrease in the number of admissions in the hospital To observe a decrease in the…

A combined physical exercise and psychosocial training program to improve physical fitness in children with cancer.

The proposed study is part of a larger KWF program proposal: the Alpe d*HuZes Cancer Rehabilitation Research Program (A-CaRe) coordinated by the EMGO Institute. The aim of the study is to evaluate the short- and long-term effectiveness of a combined…

Dendritic cell vaccination in patients with Lynch Syndrome or colorectal cancer with MSI

The primary objective is the safety and feasibility of CEA/frameshift derived neopeptide loaded DC in patient with MSI-positive colorectal cancer and persons who are known to be carrier of a germline MMR-gene mutation with no signs of disease yet.…

Prospective, randomized, pharmacological intervention study; evaluating the effect of the angiotensin II-receptor (AT1) blocker candesartan versus placebo in prevention of trastuzumab-associated cardiotoxicity in patients with primary breast cancer treated with trastuzumab

Primary objectives:1) To determine whether concurrent ATII-antagonist treatment can prevent trastuzumab-related cardiotoxicity, defined as a decline in LVEF of more than 15% or a decrease to an absolute value <45%Secondary objectives:1) To…

Cancer aftercare in general practice - A blended lifestyle medicine approach

The primary objective of this research is to gain insight into the short term (6 months) and long term (12 months) effects of the blended care protocol on cancer survivors* lifestyle behaviours. The secondary goal of this research is to gain insight…

CARE-FIT: Comprehensive AppRoach for Embedding lifestyle support in oncology care - Focusing on Increasing physical activity, better sleep and reducing stress Through eHealth

The primary aim of this study is to investigate the effects on PA, sleep, stress, health and QoL of a tailored eHealth intervention for cancer patients when embedded in oncological care. Additional aims are to gain insight into the cost-…