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Effectiveness of continuous glucose monitoring during diabetic pregnancy

In the present proposal, we aim to assess the cost-effectiveness of the use of CGMS in diabetic pregnancies.

The effect of continuous glucose monitoring on glycaemic control in patients undergoing major surgery

Our objectives are to evaluate whether CGM improves perioperative glycaemic control.

The effects of 4 weeks oral administration of omega-3 fatty acids on hepatic steatosis and insulin sensitivity in morbidly obese patients undergoing gastric bypass surgery.

The aim of this study is to evaluate the effect of supplementation of a high oral dose of omega-3 fatty acids on hepatic steatosis and glucose metabolism in morbidly obese patients undergoing laparoscopic Roux-Y gastric bypass surgery (LRYGBP).

Increasing habitual physical activity to reduce the surgical risk of hyperglycemia and complications in patients with the metabolic syndrome

In the POSitive project we aim to investigate whether the diagnosis of the metabolic syndrome could be embedded in the clinical practice of the POS. The use of the POS clinic as screening platform for health prevention contributes to early case…

Peri-operative Accuracy and Safety of Real Time Continuous Glucose Monitoring System in cardiac surgical patients. A pilot study

The primary objective of this study is to investigate the peri-operative accuracy and safety of the RT-CGMS in cardiac surgical patients.The secondary objective is to identify and define possible factors interfering with reliable and adequate…

Metformin vs Control to prevent gestational diabetes mellitus (GDM) in women with a high risk for GDM, an open label randomized controlled trial. The Medico-GDM trial.

The primary objective is to compare metformin versus no intervention for incidence of GDM in women with a high risk for GDM. The main secondary objective is pregnancy outcome with Metformin, neonatal outcomes and neonatal complications.

Randomised Controlled Study to Evaluate the Impact of Novel Glucose Sensing Technology on Hypoglycaemia in Type 1 Diabetes.

The primary objective of this study is to demonstrate the impact on time in hypoglycaemia (number of hours per day of hypoglycaemic excursions < 3.9 mmol/L, 70 mg/dL) using the Abbott Sensor Based Glucose Monitoring System compared to Self…

TANGO-DM: Randomized trial of effective treatment according to new GDM criteria

To evaluate the effectiveness and cost-effectiveness of intensive GDM treatment as compared to routine maternity care in pregnant women with a discordant OGTT result between the new (2013) WHO criteria as compared to the old (1999) WHO criteria for…

Combined effects of SGLT2 inhibition and GLP-1 receptor agonism on food intake, body weight and central satiety and reward circuits in obese T2DM patients

Primary objective:To investigate the separate and combined actions of the SGLT2 inhibitor dapagliflozin and GLP-1 receptor agonist exenatide on activity in central reward and satiety circuits in response to food related stimuli in obese patients…