704 results
To study the effects and costs of the total individual CBT package and one of the components of the total CBT treatment package (i.e. mindfulness training) in a group format compared to Treatment-as-Usual (TAU) on the short and long term.
The goal of this project is to develop and test a digital file that is expected to improve the communication between professional caregivers (endocrinologists, nurses, dietitians, social workers, psychologists). Additionally, the communication…
Transmural care for hand eczema. A randomized controlled trial with an economic evaluation alongside
1) To develop and implement a protocol for transmural, multidiscplinary care for hand eczema, coordianted by a case-manager.2) To evaluate the (cost)effectiveness of the multidisciplinary protocol for transmural care in hand eczema
Improvement of the discomfort of the paresthesia, as experienced by the patient.
Primary:The primary objective of this study is to evaluate the efficacy of LDX administered as a daily morning dose (30, 50, and 70mg/day) compared to placebo over the course of 7 weeks. This study will enrol children and adolescents (6-17 years of…
Both in emergency departments and in prehospital services (ambulances and MMTs) effort is being done to find a fast alternative for the screw-tipped bone needle that has the least amount of risk and complications.The aim of this study is to analyse…
To evaluate the efficacy of inhaled rhDNase in addition to conventional treatment in children with an atelectasis during mechanical ventilation.
Objective: to determine whether botulinum toxin A (btA) injections, intensive bimanual skill training, or a combination of both leads to more and better use of the affected arm in hemiparetic children in play, leisure time, school and personal care.
To prove the efficacy and safety of ethanol lock solution in preventing catheter-related infections and subsequently venous thrombosis in children with a malignant disease who will have a tunnelled central venous catheter inserted.
During the course of the study 2 randomisation questions will be adressed. Both questions concern patients in the high risk group.Randomisation question 1: Will the addition of Doxorubicin to the first 4 standard IVA chemotherapy courses lead to a…
We hypothesize that cognitive behavioural family intervention will be more effective compared to standard treatment in regard to the perception of FAP and resolution of co morbid internalizing psychopathology.
The objective of this project is examining whether the empowerment program POWER reduces the risk on marginalization of youngsters from immigrant families (with an elevated risk).In this project the following research questions will be answered.(1)…
Hypothesis: the Internet guided self-help intervention is effective in reducing depressive and anxiety symptoms in adolescents compared to a waiting-list control group.
Decrease the number of days complaints from MTSS through wearing of a compression sleeve or physical therapy exercises (strengthning and stretching of the calf muscle with additionally balance exercises of the ankle).
Our aim is to find methods to effectively remineralize caries lesions that have developed during orthodontic treatment. A secondary aim is to study the effect of fixed orthodontic appliances on the plaque ecology in relation to caries development in…
To characterize the multiple-dose pharmacokinetics of varenicline in adolescent maleand female smoking subjects
One of the recommendations of NICE for future research is comparing the effects of various psychological treatments for depression in youths. In particular, there is a need for studies in which parents are involved in the treatment (Birmaher et al…
The aim of the study is to investigate if alarm treatment in combination with EMDR is a better method for persistent enuresis nocturna than only alarm treatment.Subquestions: 1. What is the success percentage of EMDR with alarm treatment? 2. If EMDR…
To show that there is a significant difference in satisfaction between both reduction techniques of the doctor (difficulty) and patient (pain, duration and contence). Expected is that the technique according to Caldwell has better satisfaction than…
1) To investigate the efficacy of EEG-neurofeedback in reducing behavioral symptoms of ADHD.2) To investigate whether EEG-neurofeedback is able to improve neurocognitive functioning. 3) To investigate whether EEG-neurofeedback is able to improve…