32 results
The objective of this study is to evaluate the effectiveness and cost-effectiveness of surgical and conservative treatment of non-obstructive meniscal injuries in older patientsHypothesis: We assume equal improvement of physical function in both…
The primary aim of the study is (i) to assess the effect of a soft brace on pain, knee stability and activity limitations. Secondary aims are (ii) to assess the difference in effect of two knee soft braces (i.e., non-tight and tight) on pain and…
The objective of this feasibility study is compare the smart AFO + standardized shoes to subjects* own AFO + own shoes. Subjects* experiences with the orthotic devices will be evaluated and points for improvement will be asked. Subjects* performance…
The objective of the study is to find answers on the research question: does activation of descending nociceptive inhibitory mechanisms via central pain medication lead to changes in kinematic and/or muscular changes in shoulder function?
In the current study we want to further explore the predictability of pre-treatment pain variability on the probability to experience pain relief. Knowledge on the understanding of individual differences in analgesic properties of a drug is of…
The purpose of the study is to investigate how quickly and to what extent BAY 1834845 is absorbed and eliminated from the body (this is called pharmacokinetics). In both study parts it will also be investigated to what extent BAY 1834845 is…
What is the influence of the Rebound Hip and Newport 4 hip brace on restricting the movements that are associated with hip dislocation after at total hip replacement.
To investigate whether adding a rocker bar (including rounded heel, proximally placed fulcrum and stiffened sole) significantly reduces pain, the range of motion in the ankle and the ankle moments in patients with posttraumatic ankle arthritis.
The primary objective is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of RA in subjects with active RA who are refractory to an anti-TNF Alpha agent. The secondary objectives are to assess the following…
measuring the efficicy of the combination of green lipped mussel, curcumin and ribus nigrum (supplement Synofit) on quality of life and pain in patients with osteoarthritis of the knee
The purpose of the study is to investigate to what extent the FTS patches are tolerated. It will also be investigated how quickly and to what extent flurbiprofen from the FTS patch is absorbed and eliminated from the body (this is called…
Primary Objective: Determining the effect of a patellar strap and sports tape on pain and sport participation in subjects with patellar tendinopathy. Secondary Objective(s): Determining the relationship between injury specific, sports related and…
The objective of this pilot study is to demonstrate that NAVA ventilation is superior compared to pressure support and pressure control ventilation in work of breathing (expressed as pressure-time product) patient ventilator synchrony and other…
The primary objective in this study is to compare the effectiveness of lateral C1-2 pulsed radiofrequency application (LPRF) in comparison with conventional C3-5 facet denervation (MBRF) in patients with clinically defined cervicogenic headache.
The purpose of the study is to investigate whether the cyclodextrin added to the cholecalciferol formulation has an effect on the vitamin D3 availability in the body. Thus, it will be investigated if concentrations of vitamin D3 that are found in…
(1) To analyze differences in pain and function in patients with CMC-1 osteoarthritis after application of a custom made orthosis and an off-the-shelf orthosis (Push brace) (2) To measure compliance and factors influencing compliance with splint…
The primary objective(s) of this study is:- To determine the relative bioavailability of etoricoxib 120 mg tablets manufactured at Frosst Iberica, Spain and Elkton, VA, USA.
To investigate the effect of suppletion of vitamin D on aspecific musculo-skeletal disorders
Primary Objective: Getting insight in the effect of the use of the Genupoint patellar strap on knee joint proprioception in subjects with patellar tendinopathy.Secondary Objective(s): Getting insight in the effect of the use of the Genupoint…
Primary objective:The purpose of this study is to evaluate the short term effect of a patellar strap on symptoms and sports participation in children with Osgood-Schlatter disease.Secondary objective: The second objective of this study is to…