307 results
Our main aim for the future is to improve diagnostic testing for FLIA. NIRS and pedal force measurements are very promising in this respect, since they may be used in a clinical setting, in a research laboratory, and in the field in a high-…
(1) Determine the prevalence of (asymptomatic) silent brain infarcts among patients with COVID-19 admitted to after discharge (at least <3 months after positive PCR test) from the hospital, compared with healthy controls.(2) Investigate risk…
Since high cholesterol is a major riskfactor for cardiovascular disease we will select patients with inhirated elevated cholesterol (familial hypercholesterolemia. We want to evaluate the long term effect of cholesterol lowering treatment on the…
The goal is to get a better understanding about the role of innate immune cells and the development of ASCVD in obese subjects. We will look at the innate immune cells in blood and at the progenitor cells derived from the bonemarrow.
Primary Objective:To investigate whether arterial microcalcification (18F-NaF-PET detected) and macrocalcification (CT detected) are increased in patients with T2D who have macroalbuminuria as compared to patients with normoalbuminuria.Secondary…
The main objective of this study is to compare upper extremity dysfunction following slender TRPCI using small bore catheters (*5F) compared to standard PCI using regular size guiding catheters(*6F) and conventional stent techniques. Secondary…
Objective and Research QuestionsTo identify predictors of brain outcomes in HHT patients, we propose to leverage our multicenter network of HHT Centers to characterize comprehensive brain outcomes.Study Aims:Aim 1: We hypothesize that the presence…
To improve our understanding on the etiology of proximal DVTs, to identify risk factors for stent reinterventions and to optimize treatment after a venous stent. To improve patient education and expectation after a venous stent.
- The technical feasibility of multispectral optoacoustic tomography for the localization and assessment of disease-specific tissue in a particular anatomical area- Detection of endogenous biomarkers for the characterization in a variety of diseases
Primary aim: Examine whether and to what extent fatigue and quality of life of patients with SAH improve after participating in RE-SAB.Secundary aims: (1) Examine whether and to what extent physical activity level, physical fitness, coping style,…
The objective of this study is to compare OCT-A findings between five groups of non-glaucomatous subjects characterised respectively by a) low symptomatic, b) low asymptomatic, c) normal asymptomatic, d) untreated high asymptomatic, and e) treated…
The main objective of this study is to compare calcification promoting and inhibiting factors and their interactions in the serum of PXE patients and healthy controls. Secondary objectives (optional) are:1) to identify differences in cognitive…
Primary Objective: To assess which measures of microvascular function on 7T MRI are affected in patients with symptomatic SVDs, relative to controlsSecondary Objective(s): To establish how microvascular function relates to:• parenchymal lesion…
We aim to assess the association between (cardio-)vascular and hemodynamic factors in relation to cognitive function.
Our main objective is to improve the level of SDM during vascular surgical consultations in which a treatment decision is to be made, with the use of DSTs. Our secondary objectives are to improve SDM as experienced by both patients and physicians,…
The goal of this study is to investigate whether BOLD MRI can predict the occurrence of buttock claudication after coiling of the internal iliac arty. The BOLD technique will be used to measure blood supply parameters of the gluteal muscle during…
In this study the primary objective is to investigate whether activation of TRPV1, TRPA1 and TRPM3 by selective channel agonists induces vasodilation in human dermal arteries. If the primary objective is achieved, the secondary objective is to…
Primary objective:* To investigate the consequences of (recurrent) hypoglycaemia on inflammatory responsesSecondary objectives:* To study the atherogenic consequences of (recurrent) hypoglycaemia* To study the molecular mechanisms involved in the…
To investigate the interrelatedness between clonal hematopoiesis of indeterminate potential (CHIP) and trained immunity.
Primary objective: Compare characteristics of endothelium from older individuals with or without previous unprovoked VTE.Secondary objectives: 1) Determine the blood plasma proteome between the different groups and 2) to evaluate the prothrombotic…