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Enzyme substitution in exocrine pancreatic insufficiency; Self administration against a fixed dose regimen.

To assess the difference in efficacy of pancreatic enzymes in a self-dosage regimen after extensive patient-education in comparison to the standard treatment for patients with EPI.

APpendix derived PAncreatic cancer Reactive T-lymphocytes

To evaluate anti-tumor activity of T-cells in the GALT of patients with PDAC.

AXIOMA: Hot AXIOS metal stent for infected walled-off pancreatic necrosis management.

Investigate whether the use of the Hot AXIOS lumen apposing metal stent is superior to standard plastic pigtails stents for drainage of infected pancreatic necrosis.