14 results
The research objective is to investigate the sensitivity, specificity, and predictive values of the delirium monitor based on 4 standardized EEG electrodes who record brain activity.
The overall objective of this study is to identify valid biomarkers for POD/POCD.
To assess in vivo microglial activation (as a validated marker of neuroinflammation) using PET-CT and associated neuropsychological characteristics in patients recovered from sepsis associated delirium.
To determine an increased risk of falling during a delirium
Primary objective1. To examine the association between the use of haloperidol and the acute changes in serum glucose and QT interval in elderly patients undergoing orthopaedic surgery.Secondary objectives1.To examine the association between the use…
Primary objective 1. To examine the association between the use of haloperidol and the acute changes in fastening serum glucose and QT interval in elderly patients undergoing surgery. Secondary objectives 1.To examine the association between the use…
To study the relationship between (a) abnormal concentrations of plasma amino-acids, pterins, HVA and inflammatory parameters and (b) the severity, duration and outcome of delirium. To find a biochemical profile that predicts the occurrence of a…
This research project aims at quantification of the efficacy and (cost-) effectiveness of the Hospital Elder Life Programme (HELP) in the Dutch health care situation. Furthermore, this project will describe and understand the experiences of patients…
To determine the differences in EEG properties between delirious and non-delirious (ICU) cardiothoracic surgery patients surgery and to determine the EEG deviation where the largest differences appear. Secondary objective is to determine the…
The main aims of the proposed study were (1) to determine the effect of delirium on cognitive-, psychological-, functional-, and health outcomes at discharge, 3, 6 and 12 month follow-up. Patients with a delirium at admission will be compared with…
Primary objective:To compare the mean absolute glucose change in postoperative older patients with and without a delirium.Secondary objectives:1. To compare the mean glucose concentration and glucose variability in postoperative older patients with…
Our primary aim is to tackle the factors of frailty in an early phase, which is possible in elective planned surgery. We hypothesise that optimal preparation, starting 5 weeks before surgery, will reduce the incidence of delirium from 15 % to 7.5…
Primary questions: 1) Is there a significant difference between the postoperative levels of 6-sulfatoxymelatonin (6-SMT, metabolite of melatonine) in 24 hour urine samples, in elderly patients with traumatic hip fractures, with and without a…
The DEPTHip Study aims to shed light on the question whether the use of a continuous ultrasound-guided FICB employing catheter technique, administered in the ED within 2 hours after presentation of an elderly patient with a hip fracture, can…