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Tapering antidepressants in pregnancy: A pragmatic multicenter RCT to investigate risk and benefits for mother and child.

The aim of this study is to investigate the effect of guided tapering in early pregnancy as compared to continuation of SSRIs during pregnancy. We will study effects on both mother and child with a pragmatic approach.

Quality of life in the postoperative course of bariatric surgery: a role for diabetes?

1) To investigate the impact of keeping/loosing diabetes on quality of life and psychological well-being in a group of (morbidly) obese patients who underwent bariatric surgery, and 2) To explore whether we can predict postoperative quality of life…

PSYCHE-ICD study
(Psychiatric SYmptoms in Congestive Heart failure: Evaluation in ICD recipients)

The primary objective of the study is to relate depression and anxiety in CHF patients receiving an ICD to the occurrence of ventricular tachyarrhythmias. Secondary objectives of the study are:Assessment of the effects of depression and anxiety on…

Molecular underpinning of light therapy in seasonal affective disorder

Link inter-individual differences in light sensitivity (measured by melatonin suppression) to molecular pathways in primary fibroblasts in SAD patients and healthy controls and with light therapy succes in SAD patients and with gene variation in two…

Acceptance and Commitment Therapy as a self-help intervention for adults with mild to moderate psychological distress: a randomized controlled trial

The purpose of the study is to conduct a randomized controlled trial with the self-help intervention *Voluit leven* for adults with mild to moderate psychological distress. The research question is: What are the effects of the preventive self-help…

*The Neural Correlates of Mood-Congruent Memory Bias in Major Depressive Disorders*

To investigate the maintaining factor of mood-congruent memory bias of depression, the circumstances when they occur and the neural correlates of these.

The evaluation of a group therapy for patients with depressive symptoms after stroke - a pilot study

The objective of the study is to investigate the effect of the *Coping with depressive symptoms after stroke* course on depressive symptoms and quality of life in a waiting list controlled study.

Multi-country cOllaborative project on the rOle of Diet, FOod-related behaviour, and
Obesity in the prevention of Depression (MooDFOOD)

The main objectives of the trial are* To develop innovative evidence*based, feasible, effective and sustainable nutritional strategies for the prevention of depression in EU citizens.* To establish the feasibility and effectiveness of nutritional…

PCT after rTMS for relapse prevention of depression

This pilot study aims to establish the feasibility of offering PCT live or online to MDD patients in remission due to rTMS by measuring treatment adherence using descriptive data and daily affect. Results will be used to improve patient compliance…

ICare Prevent * an Internet -and Mobile based Self-help Intervention for the Indicated Prevention of Depression and Anxiety

The objective is to investigate the effectiveness of an Internet-based self-help intervention for people with mild symptoms of anxiety and/or depression. This intervention will be offered with and without guidance and will be compared to usual care…