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Grumpy or depressed? Disentangling normative irritability from early signs of depression among adolescents with cell-phone micro-measures of daily mood swings.

Objective: We would like to differentiate *normative mood swings*. in adolescence from early signs of depression. A comparison between low-risk adolescents and an at risk and a clinically referred sample is needed to detect an unrecognized subsample…

Diagnostic Imaging of Affective Disorders using Emotion-processing in non-depressed patients
(DIADE-II).
A neuroimaging study to determine biomarkers to discriminate unipolar and bipolar depression

We aim to (1) improve differential diagnosis of recurrent MDD and BD by investigating biomarkers at a neuropsychological and neurobiological level ; (2) investigate whether affective neuropsychological testing can be used as a diagnosios tool for…

The relation between free serotonin in plasma, serotonin in trombocytes and the genotype of the serotonin transporter in carcinoid patients, patients on selective serotonin reuptake inhibitors and healthy controls.

To determine the influence of the serotonin transporter activity on the plasma free serotonin and dopamine amount and the stored amount (in trombocytes) in three different populations (healthy controls, carcinoid patients and patients on medication…

Attentional processes in depressed and non-depressed adolescents

1) To examine whether adolescents with depression, show abnormalities during specific attentional processes, compared to normal controls, 2) To determine whether abnormalities in attentional processes can be considered as prognostic markers of a…

Effects and costs of a combined screening and treatment program
for elderly (aged 75 years and over) with depressive symptoms
in general practice

To study the effects and costs of a screening and treatment program for elderly with depressive symptoms in general practice.

Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in iRritable bowel syndrome In Europe

Primary Objective: The overarching goal of the multicentre trial is to characterize the overlap between mental and non-mental comorbid conditions of IBS. In IBS and patient control groups we will characterize depression, anxiety, fibromyalgia and…