36 results
To investigate of the accelerated aging process in morbid obese individuals can be stopped or reversed by bariatric surgery. We also want to investigate whether the aging process in muscle tissue, liver tissue and fat tissue is comparable to the…
1. To investigate the impact of various resistance-type exercise variables (i.e. load, repetitions, volume) on skeletal muscle mass, strength and physical performance outcomes in (mal)nourished frail community-dwelling older adults.2. To investigate…
The aim of our study is to investigate whether a tailored nutritional care follow-up program in children who are being discharged from the hospital with nutritional support improves nutritional intake and status as well as feeding behaviour and…
Primary Objective: Main aim of the study is to investigate in detail the differences in gene expression, body composition, muscle function and muscle metabolism in colon cancer patients compared to controls. Secondary objectives:Secondary aim of the…
To implement and assess the feasibility, efficacy and safety of bariatric surgery in adolescents with severe obesity together with a multidisciplinary care pathway around the procedure.
The objective of the study is to determine the difference in brain responses after consumption of processed and unprocessed food between healthy lean subjects with a *normal* eating pattern with that of Binge Eating Disorder (BED) patients, who are…
The primary objective of this cohort study is to determine the prevalence of simple and progressed NAFLD in subjects at risk followed by the general practitioner The secondary objectives are:1. To study the factors linked to the development of NAFLD…
Our primary objective of the feasibility study is to assess the acceptability and feasibility of the developed 2EAT dietary treatment in older adults with obesity. The primary objective the main study (RCT) is to investigate whether a shift towards…
The current study aims to investigate two types of preventive interventions in night shift workers: a personalised sleep intervention and a personalised nutritional intervention. It will assess the effects of the two interventions on sleep and on (…
To assess kidney oxygenation in obese, hyperfiltering adults with T2D before and after bariatric surgery for men and women separately determined by BOLD-MRI
To assess changes in food intake and food preference (e.g., fat and sugar) after bariatric surgery.
This protocol involves studies that aim at:1. A better understanding of sensory perception and eating behaviour2. Validation of newly developed sensory and behavioural methods3. To determine the effect of fat, sugar and/or salt reduction on sensory…
We aim to determine the differences in oral and intestinal microbial composition between community-dwelling older adults with and without malnutrition, further stratified to those with and without poor appetite.
To study activity in the reward-circuitry of the brain in patients suffering from cachexia induced by cancer.
Primary objective- To compare the efficacy of liraglutide versus placebo on weight loss in obese paediatric subjects with PWS at 16 weeks and versus no treatment at 52 weeks.Secondary objectives - To compare the efficacy of liraglutide versus…
Deep Brain Stimulation in Patients with Chronic Treatment Refractory Anorexia Nervosa: a Pilot Study
The aims of this research project are:1) to establish the efficacy and feasibility of DBS as a last resort treatment in patients with chronic, treatment refractory AN. 2) to associate the efficacy and functional effects of DBS in patients with…