18 results
To demonstrate that combined (repeated) laser photocoagulation prolongs time to failure compared to anti-VEGF monotherapy.
Primary objective:To demonstrate that the mean change from baseline in Best Corrected Visual Acuity (BCVA) over a 12 month treatment period obtained with either a 0.5 mg ranibizumab *Treat and Extend* (TE) dosing regimen with adjunctive laser, and/…
Primary: efficacy, assessed by best-corrected visual acuity and SD-OCT of 1 eye (*study eye*). Secondary: retina anatomy of the study eye, safety and tolerability, PK, PD.Exploratory: Best-corrected visual acuity, SD-OCT and retina anatomy of the…
Primary objective:- To determine whether high dose vitamin D treatment in optic neuritis can reduce axonal loss as measured by OCT. Secondary objectives: - To investigate whether the occurrence of a second attack (defining clinically definite MS) is…
To demonstrate that CLT is more sensitive for keratoconus detection compared to other corneal topography methods.
This study aims to gain insights in the pathogenesis of idiopathic orbital inflammation, with ultimately a directer and more effective therapy.
To demonstrate non-inferiority of continuation of platelet inhibiting drugs in eyelid surgery regarding the risk of haemorrhagic complications.
To show non-inferiority in success rate of the lateral eyelid block excision compared to the lateral tarsal strip.
This study aims to gain insights in the pathogenesis of idiopathic orbital inflammation, with ultimately a directer and more effective therapy.
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The primary objective of the study is to evaluate the safety and efficacy of Anecortave Acetate Depot (3, 15 or 30 mg) when administered by AJD for treatment of elevated IOP following intravitreal steroid therapy.
Our objective is to find predictive biomarkers for disease progression in RVCL-S, a monogenetic small vessel disease, and to dissect disease mechanism to identify new treatment targets to improve health for RVCL-S patients, which may also serve as…
The VAT project is set out to prove that this approach is superior and that the Quality of Life of children with amblyopia might be significantly improved in comparison to occlusion therapy.
This study has been transitioned to CTIS with ID 2024-512244-36-00 check the CTIS register for the current data. The objectives of this are to establish the safety, tolerability, and efficacy of VRDN-001, and the pharmacokinetic (PK) and…
To evaluate the effect of lidocaine temperature on pain perception during infiltration for upper blepharoplasty.
To demonstrate that DMEK is superior to DSAEK with respect to visual acuity and quality of vision.
Primary Objective: Compare visual acuity between adults born prematurely and adults of general population born at full term.Secondary Objective(s): o Compare other anatomical and functional ocular outcomes (retina, macula thickness, refraction,…
Primary Objectives: - Assess the feasibility and clinical value of 7T MR to provide a more detailed anatomic description of the anterior visual pathway in NFMA patients compared to conventional MRI. - Assess the feasibility of high-field MRI to…