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A Phase 2, Multicenter, Randomized, Active-Controlled, Parallel-Group, Dose-Finding and Safety Study of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2)/Calcium Phosphate Matrix (CPM) in Subjects With Decreased Bone Mineral Density.

Onset of effect of systemic therapy to enhance bone density (eg, bisphosphonates) is not immediate and may not adequately protect subjects with decreased bone density from fracture.Bisphosphonate therapy will typically require 2 to 3 years of active…

ReValidate! The effect of a serious game compared to standard therapy for rehabilitation after distal radius fractures

To determine the effectiveness of the use of a serious game as a therapeutic tool for wrist rehabilitation after treatment of a closed distal radius fracture, in comparison to standard therapy. The effects on reported functional outcomes of…