27 results
The primary objective is to evaluate the difference in 68Ga-exendin tracer accumulation in the pancreas of patients with and without complete resolution of T2DM after RYGB by quantitative analysis of PET images.
The main objective is to examine if 68Ga-exendin tracer accumulation (i.e. beta cell mass) differs in patients with persisting HH after RYGB compared to matched patients without HH after RYGB. The secondary objectives are:- compare GLP1 and GIP…
- To determine whether there is a mitigated immediate immune response to islet infusion in immunosuppressed recipients- To determine if complement activation during immediate immune response is affected in immunocompromised recipients
In the present proposal, we aim to assess the cost-effectiveness of the use of CGMS in diabetic pregnancies.
Pilot study to test the feasibility of measuring glucose uptake in adipose tissue under hyperinsulinemic hypo- ande euglycaemic conditions to quantify the effect of hypoglycaemia on metabolic activity of adipose tissue (VAT, SAT and GFAT) in…
Our objectives are to evaluate whether CGM improves perioperative glycaemic control.
The objective of this study is to investigate the effect of broccoli seedlings on postprandial inflammatory parameters and insulin sensitivity after an oral glucose load (dual isotope technique) and monitoring the bioavailability and kinetics of SFN…
Substudy A• Validating the supramaximal SteepRamp exercise test to determine physical fitness in type 2 diabetes patients by correlating the result with a conventional VO2max exercise test and determining the test-retest reliability.Substudy B•…
To determine whether patients with Type 1 diabetes mellitus in sub-optimal glycemic control can achieve better glycemic control as evidenced by a drop in HbA1c using the Medtronic MiniMed Paradigm® REAL-Time Pump and the continuous Glucose…
Following the participants three more years will enable us to get a better overview of the consequences of the screening with regard to treatment, health, lifestyle modifications and illness perception with regard to obesity. Primary Objective: • To…
The primary objective is to study if non-diabetic patients with biopsy-proven NASH have higher hepatic FDG-uptake as compared to non-diabetic patients with biopsy-proven non-inflammatory steatosis?Secondary Objectives are (1) to study the…
Main objective:Have formerly preeclamptic women, 5 to 10 years post-partum, a higher prevalence of a cardiovascular riskprofile compared to women with uncomplicated pregancies in history.
The primary objective of this study is to investigate the peri-operative accuracy and safety of the RT-CGMS in cardiac surgical patients.The secondary objective is to identify and define possible factors interfering with reliable and adequate…
The primary objective of this study is to demonstrate the impact on time in hypoglycaemia (number of hours per day of hypoglycaemic excursions < 3.9 mmol/L, 70 mg/dL) using the Abbott Sensor Based Glucose Monitoring System compared to Self…
High-field (7T) MRI and genetic biomarkers for neurocognitive impairment in type 2 diabetes melltius
The primary objectives: 1. To tailor and apply high-field multi-parametric and functional MRI techniques to identify cerebral biomarkers in DM2 and MetS patients compared to control subjects.2. To examine a specific set of genetic hypotheses in DM2…
Primary Objectives: 1. To tailor and apply multi-parametric, functional MRI techniques to identify cerebral abnormalities (cerebral biomarkers) in MELAS patients.2. To investigate which cerebral biomarkers are shared and differ between MELAS…
Primary objective: Assessment of the impact of the reference glucose measurement on the measured performance of a CGM system, comparing regular venous and arterialized-venous reference glucose samples.Secondary objective: - Assessment of the impact…
The study objective is to compare the pituitary uptake of 68Ga-NODAGA-exendin in patients with and without adequate response (based on HbA1c or weight loss or classification by the treating diabetologist) to GLP-1R agonist treatment, to increase…
Primary Objective: Compare the uptake of 68Ga-NODAGA-exendin-4 in the liver between T1D patients with functional islet grafts (C-peptide > 0.8 nmol/L after mixed meal stimulation test and relevant laboratory parameters as HbA1C and exogenous…
The study objective is to measure beta cell mass and function in subjects with type 1 diabetes during and shortly after the honeymoon phase, to determine whether the change in metabolic control is mainly caused by a decrease in the total number of…