48 results
The main objective is to test if PH occurs in patients treated with thoracic radiotherapy and identify dose metrics and other risk factors for the development of PH after thoracic radiotherapy. In addition, changes in systolic and diastolic…
The overall aim is to improve therapy and prognosis in patients with GCA by improving the diagnostic process. We wish to do so by comparing 3 imaging techniques in a cross-sectional manner. The following goal was formulated:To compare validity and…
The objective of this study is to determine the mass balance and routes of excretion of total radioactivity after a single oral 25 mg dose of [14C]BAY 2433334 given as solution. For further clinical development, human mass balance data are required…
To investigate if participation in a moderate to high-intensity exercise program during adjuvant chemotherapy has reduced cardiovascular toxicity in women with breast cancer after an average follow-up of 6 years.
The aim of our study is to develop a new PRO instrument for acute and chronic wounds. Our 3-phased approach involves a qualitative study, an international field-test and a psychometric study. Patients, healthcare providers and other stakeholders…
As patients with congenital vascular malformations often suffer from severe pain and morbidity due to the vascular malformation, quality of life is often signifcantly impaired. The primairy objective of the present study is to reduce pain complaints…
The purpose of the study is to investigate how quickly and to what extent BIA 5 1058 is absorbed, distributed, metabolized (broken down) and eliminated from the body (this is called pharmacokinetics). The investigational compound will be labeled…
Aim 1: Confirm the hypothesis that the IgG4 qPCR test score correlates with disease activity in vasculitis as observed in the pilot study. Aim 2: Study IgG4-expressing B-cells from blood of vasculitis patients to understand their role in the…