23 results
The effect of pulse rate on temporal resolution and speech intelligibility in cochlear implant users
To determine the (in)direct effect of CI pulse rate on speech intelligibility by means of (1) a standard test for temporal resolution: amplitude modulation detection (AMD) at two different modulation frequencies, (2) speech intelligibility tests (…
The objectives of this study are to evaluate the clinical outcome of a cochlear implant (CI) over standard health care therapy with either BAHA or CROSS in patients with SSD and to examine the cost efficiency of cochlear implantation in these…
To further optimize 7.0 Tesla MRI techniques and to develop new MRI techniques that will enable state-of-the-art clinical and cognitive research leading to improved patient care. Whereas some applications of 7.0 Tesla MRI already show improvements…
In this research, psychofysical tests will be used to explore in which way the signal processing in CI and hearing aid can be optimized to fully exploit both input modalities in speech understanding, and in sound localization..
To evaluate the efficacy of various masking strategies in cochlear implants as a treatment for tinnitus in patients with profound hearing loss.
to measure neural activity of the central nervous system in tinnitus related brain areas in cochlear implant recipients with chronic tinnitus and to determine the relation between this neural activity and the subjective tinnitus experience of…
Primary objective: to investigate the prevalence of vestibulotoxicity and disturbance of equilibrium as far a Cystic Fibrosis patients with at least one treatment with tobramycin are concerned. Secondary objective: To formulate an advice for…
The primary objective is to clarify the frequency of t-BPPV in patients after mild TBI. Secondary objectives are: assessment of the symptoms of t-BPPV and the treatment success of t-BPPV.
The main objective of the study is to better explain disappointing speech recognition in individual cases, with as ultimate goal to find optimal individual settings for the sound processor (outside the scope of this project). We test two new methods…
To determine the sensitivity and specificity of the HINTS+ test in detecting a central cause in patients with acute onset, continuous dizziness in a general ED population, when performed by general neurologists/ED physicians.
The aim of this study is to measure eCAPs intraoperatively (and perform electrocochleography [ECochG] in case of any residual hearing) and to estimate cochlear health in these patients by applying insights gained from our guinea pig experiments.
To evaluate the vestibular function relating results to surgery, radiotherapy, active surveillance, intratympanic gentamicin, and intratympanic gentamicin followed by active treatment based on objective vestibular testing and dizziness related QoL.
The primary objective is to investigate the course of limitations in physical activity and daily functioning in patients who are diagnosed with unilateral or bilateral vestibular hypofunction, and to identify factors that are associated with this…
This study has been transitioned to CTIS with ID 2024-512860-75-00 check the CTIS register for the current data. The aim of this feasibility study is to validate pre-treatment [89Zr]-bevacizumab PET/CT as an imaging biomarker for prediction of…
Primary aimTo determine the prevalence of children with hearing loss at time of discontinuation of cancer therapy in a prospective full cohort of 600 children with solid and CNS tumors.The secondary objectives of this study are:- To study the…
1. Monitoring of auditory function during destructive labyrinth surgery to study hearing preservation and vestibular implantation2. Monitoring of vestibular function during destructive labyrinth surgery to study better electrode position and…
The primary objective is to study the impact of continuous vibrotactile feedback during waking hours in daily life on balance, (fear of) falling, fatigue, and overall functioning. The secondary objective is to study the impact of a vibrotactile…
To study the human adult cochlea, in specific it*s RNA and protein expression patterns and morphology.
To explore the relation between 25-hydroxyvitamin D, HbA1c, uric acid, age, gender, duration of symptoms, a history of head trauma, vestibular neuritis, Ménière*s disease or (vestibular) migraine and the recurrence of BPPV.To assess whether changes…
1. Define diagnostic approach for patients with bilateral vestibulopathy.2. Define inclusion criteria for vestibular implantation.3. Investigate patient expectations of the vestibular implant. 4. To gain a clear insight into consumption of health…