15 results
In the present study we will evaluate the standardized care protocol developed in our outpatient clinic, intended to guide counselling for medication use prior to pregnancy. This protocol guides treatment decisions based on disease activity,…
The primary objectives of this study are to assess whether there is transfer of CZP into breastmilk of lactating mothers who are receiving an established dosing regimen of CZP by evaluatingthe concentration of CZP in mature breast milk, and to…
To compare the effectiveness of the tocolytic agents Nifedipine (a calcium channel blocking agent) versus Atosiban (an oxytocin receptor antagonist) in the improvement of neonatal outcome in women with threatened preterm labour (25-34 weeks…
The primary objective of this study is to assess whether there is transfer of CZP across theplacenta to infants from mothers by evaluating the concentration of CZP in the plasma of infants.The secondary and exploratory objectives are to assess the…
Primary objectives: -To evaluate the PK profile of OBE001 when administered orally to pregnant women.Secondary objectives: -To evaluate the maternal safety and tolerability of OBE001 when administered orally to pregnant women.-To evaluate the acute…
For women with a singleton fetus in breech presentation at term, this study answers the question if atosiban is more effective compared to fenoterol as a tocolyticum in external cephalic version
Primary outcome is to evaluate whether successful ECV is associated with maternal thyroid function and mood state in single pregnant women with breech position at end term.
To assess in term pregnant women with an unfavourable cervix (Bishop score < 6, Appendix1) the effectiveness of induction of labour with a transcervical Foley catheter as compared to induction with prostaglandins.
1. To explore the pharmacokinetics (PK) of intra-vaginal delivery of gonadorelin and oxybutynin. 2. To assess the safety and tolerability of gonadorelin and oxybutynin delivery with a prototype intra-vaginal ring.
The main objective of our research is to study the effectiveness of the SAFER pregnancy intervention in reducing risk behaviour (i.e. smoking and alcohol use) in pregnant women and women with the wish to conceive. The secondary objectives focus on…
PrimaryTo examine the pharmacokinetics of standard antibiotic regimen used at the department of Obstetrics at the Erasmus MC for postsurgical prophylaxis after caesarean section.Secondary- To examine the relation between the weight category (1. BMI…
The main objectives are to investigate whether our product is suitable for the target group, to identify barriers to wider implementation in mainstream care, and to gather patient experience and feedback. We want to know if patients perceive the…
The primary objective of this study is to expand the knowledge about pregnant women with PTSD (symptomatology). Pregnant women with PTSD (symptomatology) will be described, ass wel ass the pregnant women who develop PTSD (symptomatology) during…
Primary Objectives: Determine oncologic outcomes after fertility-sparing treatment in AYAs with cervical, ovarian or endometrial cancer (Q1). Determine fertility and obstetric outcomes after fertility-sparing treatment in AYAs with cervical, ovarian…
To examine the pharmacokinetics in maternal blood of standard regimen at the Erasmus MC of two doses of 12 mg betamethasone intramuscular with a 24 hours interval for pregnant women suspected of preterm birth with a gestational age between 23+5…