52 results
The objective of this clinical study is to assess the safety and effectiveness of the Apollo Intravascular Lithotripsy (IVL) System for lithotripsy-enhanced balloon dilatation of calcified, stenotic de novo coronary lesions prior to stenting.The…
The purpose of this study is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft System versus Gore Excluder/Excluder Conformable AAA Endoprosthesis in subjects with AAA.
The objective of this clinical study is to assess the safety and effectiveness of the Bolt IVL System for the lithotripsy-enhanced percutaneous coronary intervention of de novo, calcified, stenotic coronary lesions prior to stenting. The data is…
This study has been transitioned to CTIS with ID 2023-509710-11-00 check the CTIS register for the current data. Study Objectives:The purpose of this Phase 2 study is to evaluate the safety, efficacy, pharmacokinetics (PK),pharmacodynamics (PD), and…
Unravel the working of the immune system in South Asians, specifically the monocytes. We will also study whether the release of incretin hormones (GLP-1 and GIP) following a meal is lower in South Asians compared to Europids. The latter we will…
To assess the short-term and long-term safety and efficacy of bilateral ultrasound renal sympathetic denervation (RDN) of the native kidneys in renal transplant patients with uncontrolled hypertension.
AGELESS has 3 specific aims - they all refer to patients with carotid atherosclerosis:1. To compare patients with and without carotid intraplaque hemorrhage, as assessed with MR-Plaque Imaging, in terms of apoB, Lp(a) levels and traditional…
The goal of our study is to evaluate if it is feasible to incorporate a standardized treadmill test into the workup of a patient with an iliofemoral venous obstruction, who is planned for venous stenting, before and after the procedure. We want to…
The primary objective of this trial is to assess the efficacy of immediate CAS among patients with acute ischemic stroke treated with EVT and a severe ipsilateral proximal carotid artery stenosis (>50%) or occlusion and compare this with the…
The primary objective of this trial is to demonstrate the superiority of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis for primary patency when compared to bare metal stenting for the treatment of patients with complex iliac occlusive…
Primary objective: To compare the number of episodes of atrial fibrillation detected by the Corsano CardioWatch 287-2 during 28 days of use with the number of episodes of atrial fibrillation detected by conventional Holter monitoring during 48 hours…
Primary Objective:Our primary goal is to investigate the feasibility of a large pragmatic study of the effectiveness of a tailored MLI for patients with depression in general practice and to evaluate potential barriers and facilitators in a process…
This proof-of-concept study aims to prove the safety and feasibility of FFR in BTK lesions. Safety is defined here as conducting the FFR measurement without complications caused by the FFR measurement. Feasibility is defined here as successfully…
To determine the effects of the PCP+SM compared with usual care on BP control in adults with hypertension. To determine the effects of the PCP+SM compared with usual care on antihypertensive medication use in adults with hypertension. To determine…
To identify novel (causal) risk factors, including biomarkers and genetic determinants for disease progression and (severe) diabetes complications in people with T2D, in order to develop new, more targeted and effective therapies that will improve…
In this clinical pilot study we want to gather data in order to calculate a power for correct subject group to answer the following research question: to explore the relation between NETs/cfDNA in the blood and NETosis in burn wounds and their…
The objective of the HORIZON trial is to demonstrate and provide long-term clinical data on safety and performance of the Qmedics EXIST NiTi Stent System type FLEX & PULL for treating de novo or re-stenotic symptomatic atherosclerotic…
The aim of this study is to assess the clinical value of bedside tests compared to DUS to detect PAD in patients with diabetes-related foot ulceration, with special emphasis on the ACCmax.
To investigate whether high perceived stress is associated with inflammatory reprogramming of innate immune cells and their bone marrow progenitors, and with increased arterial wall inflammation, in subjects with an increased CVD risk.
Objective: The aim of the present study is to study the effect of increased adrenaline levels on the inflammatory response (e.g. leukocyte phenotype, cytokines, inflammatory proteins) by administering exogenous adrenaline. Secondary aims consist of…