40 results
The incidence of wound complications in endovascular aneurysm repair (EVAR). VAS scores will be obtained to objectify the advances of a percutaneous approach. Cultures and wound biopsies will be obtained from every patient. Also cost-effectiveness…
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation of the device, which may help in stent selection and in designing stent grafts that are more durable.
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
1 Assessment whether using a nerve-sparing exposure of the aortoiliac tract during vascular reconstruction will lead to a neurophysiologically intact sympathetic pathway to the intra-pelvic organs and thus to an intact postoperative function.2…
The principal goal of this study is to identify whether and how innate immune host factors predispose to the development of chronic Q-fever.
The main goal of the current study is to gain insight in the development and rupture rate of aneurysms and to detect potential markers that predict the risk of aneurysm rupture.
Primary Objective: To determine the differences in function and morphology of the distinct abdominal adipose tissue depots (e.g. SAT, PVAT, OAT and MAT; see figure 1) in patients undergoing elective open abdominal aortic surgery.Secondary…
The primary objective of the present study is to characterize the glucose metabolism in patients with SAH in the acute- and, sub acute phase and during follow-up. The secondary objectives are to relate glucose metabolism to clinical condition on…
To identify an AAA associated genes by a functional candidate gene approach.The identification of an AAA associated gene will have several impacts on this high prevalent disease:1. It will improve our understanding of the molecular pathways involved…
The aim of the study described in this protocol is the identification of genes involved in aortic aneurysm development. This will be achieved by characterization of large AA families, including pedigree investigations, diagnostic measurements (…
1) To unravel the pathogenesis of DCI by studying the time course of cerebral perfusion and vasospasm in patients with aneurysmal SAH with CT, and 2) to obtain a diagnostic tool for the detection of DCI on the basis of CT-perfusion (CTP) parameters…
The objective of the current study is to determine whether the wait-and-see policy affects anxiety levels and quality of life in patients with aortic abdominal aneurysms between 3 and 5.5 cm in diameter. Furthermore, we aim to examine the influence…
Correlation of FDG uptake and in vitro aneurysm wall tensile strength. (primary objective). The effect of aneurysm sac depressurisation, after endovascular aneurysm repair, on aneurysm wall inflammation (secondary objective).
To establish an operational reference database on intracranial aneurysms encompassing clinical and genetic data on at least 800 patients, 400 controls and 400 relatives of patients where a familial trait is recognized, together with imaging data on…
1. The application of 4D flow MR imaging to analyse blood flow patterns (flow angle, flow asymmetry), regional vessel wall parameters (regional wall shear stress, vessel wall thickness) and pulsed-wave velocity in neoaortic root, carotid artery and…
The main goal of this pilot study is to analyze if using the 7.0 Tesla MRI scanner potential markers predicting aneurysmal rupture (i.e thickness and enhancement of the aneurysmal wall) can be studied in IA patients.
The purpose of this study is to answer the following question: Leads a primary coagulation corrected with a single dose of fibrinogen concentrate after ascending aorta-arc reconstruction to a decrease in the number of allogenic blood transfusions,…
Gaining information on the dynamics and shape of the stent graft and stented target vessels, and how these change over time will improve our understanding about the fixation and/or sealing of the stent graft, which may help in stent graft selection…
This study has been transitioned to CTIS with ID 2024-517236-22-00 check the CTIS register for the current data. The main purpose of this study is to assess the hypothesis that a strategy with ASA 100mg/day and intensive blood pressure treatment (…
To compare the effects of a preoperative PA program in addition to usual care versus usual care only on the change in SB from baseline (T0) to the end of the preoperative (intervention) period (T1) in patients with TAD.