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Prophylaxis of venous thromboembolism in patients with a fracture of the lower extremity being treated conservatively with a below-knee plaster cast.

The purpose of this study is to determine the need for thromboprofylaxis in patients being treated in a below-knee plaster cast after trauma of a lower extremity and if there is, to assess if both of the two tested prophylactic treatments are suited…

Dalteparin Sodium Injection (FRAGMIN®), Multicenter, Open Label, Single-Arm, Long Term (52 weeks) Study for Understanding Safety and Efficacy in Subjects with Malignancies and symptomatic Venous Thromboembolism

The primary objective of the study is to determine the rate of majorbleeding events in cancer subjects receiving extended treatment withdalteparin (> 6 months and up to 12 months) for prevention ofrecurrent symptomatic venous thromboembolism…

Highlow study: Low-molecular-weight heparin to prevent recurrent VTE in pregnancy: a randomized controlled trial of two doses

To evaluate the efficacy and safety of intermediate dose LMWH versus fixed low dose LMWH in pregnant women with a history of previous VTE.

DOAC Levels prior to Incision study: DALI study

To measure DOAC levels just before surgery of all DOAC patients in the LUMC with elective surgery for which ceasing of DOAC treatment is required.

Prospective study into the relation between bodyweight en the effect of thrombosis prophylaxis in patients admitted to hospital

The objective of the study is to evaluate in a prospective setting the effect of body weight on anti-Xa levels in the blood after administration of prophylactic nadroparin 2850 IE to patients admitted to the hospital. Second, we want to see what the…

What is the optimal antithrombotic strategy in patients presenting with acute coronary syndrome having atrial fibrillation with indication for anticoagulants?

1. To investigate the efficacy of dual therapy (omitting acetylsalicylic acid) compared to triple therapy in patients with atrial fibrillation and acute coronary syndrome.2. To investigate the safety of dual therapy (omitting acetylsalicylic acid)…