59 results
To evaluate image quality and accuracy of detection of perfusion defects associated with pulmonary pathology on iodine maps of the lung that are created by two different CT techniques: 1. A standard of care CTPA with DECT and 2. A new technique that…
Objective 1: To prospectively evaluate the utility of C-FLOW monitor to examine status of regional CBF and reperfusion in patients presenting with acute anterior circulation ischemic stroke syndrome. Objective 2: To assess the feasibility,…
The study has two main objectives. The first objective is to estimate the extra yield in detected cases of AF in patients aged 65 years and over, using case finding. The second is to compare three methods to detect AF.
Frequency of PNH in a selection of patients with DVT. In several publications PNH has been described especially in patients with DVT and younger than 30 years of age and/or with DVT on unusual places.
Primary objective: to determine the incidence and location of thrombi in the umbilical venous catheter route during and after umbilical catheterization and in the same route in infants without umbilical catheters. Secondary objectives:A. to…
The main aim is to investigate clinical effects of different implementation methods of online supported self-management for thrombosis patients in primary care. Secondary objectives include well-being, health care use and actual use of the portal.…
The goal is to investigate wether a PNH clone could be the cause of an unexplained thrombosis. In the population of patients with unexplained thrombosis a PNH clone may be the cause.The goal is to investigate whether the prevalence of PNH clones is…
See chapter 'objectives' of study protocol (page 12)
Primary Objective: To assess the analytical performance of the cardiac reader Secondary Objective(s): To assess the user friendliness of the device (handling, analytical speed).
The main objective is to determine the effect of different anticoagulant and procoagulant agents on thrombin generation in whole blood and compare it to the effect on thrombin generation in PPP and PRP at different tissue factor concentrations. In…
Choosing the most suitable laboratory test and setting up a gold standard test to measure dabigatran. Additionally, determining maximal and minimal concentrations of the drug.
Before embarking on a study using MRDTI as sole test to manage clinically suspected UE-DVT, we need to perform a study to determine whether the test has the potential to be useful in patients with suspected UE-DVT. This study has the objective to…
Primary objectives:1. To determine image quality and diagnostic accuracy of CE-MRV using a new, optimized high resolution 3D T1 weighted volume interpolated gradient echo sequence with fat suppression (THRIVE) with both a blood pool and a…
We have set prior to the design and implementation of this research a primary and a secondary goal.Primary goal:Testing the validity of the computer model of the coagulation cascade and the related PK / PD model of VKA and heparin for use in…
This study has three objectives:1. To describe flow patterns in the left atrium in patient with sinus rhythm and atrial fibrillation. 2. To prospectively verify the data in patients with atrial fibrillation3. Correlation of abnormal flow patterns to…
Primary Objectives:To (1) Assess the feasibility and tolerability of performing US and/or contrast-enhanced MRI in children with central venous catheters (CVCs) or peripherally inserted central catheters (PICC lines); (2) assess the accuracy of US…
We aim to evaluate the use of MRDTI in the diagnosis of acute proximal DVT, comparing the findings with CUS. To evaluate the outcome of patients with positive and negative MRDTI and CUS, clinical outcome after 3 months of follow-up will be measured…
Evaluation of four clinical decision rules to exclude a pulmonary embolism (Wells rule, revised Geneva score, simplified Wells rule and the simplified revised Geneva score). Evaluation if it is safe and easy to use this rules.Beside this, the…
To assess the accuracy of the electronic nose in the diagnosis of pulmonary embolism.
To compare the clinical outcome after a first episode of VTE in patients with well-defined thrombophilia who have been identified and treated for a longer duration with anticoagulants with patients with VTE who have not been routinely tested.