91 results
This research aims the usefullness of duplex mapping in systemic giant cell vasculitis. In determing the diagnosis, the duplex will be compared with the current gold standard, the 18F-FDG PET-CT, looking at the sensitivity and specificity of the…
The aim of this project is to assess whether 4D-CTA can generate 3D cranial image data sets with sufficient spatial and temporal resolution to enable its use as a diagnostic tool in cerebrovascular pathology and physiology such as arteriovenous…
The primary objective in this observational study is to determine microcirculatory profile in preterm and term neonates. We would like to determine how the microcirculation changes in time during the phase of adaptation and correlate inter- and…
The principal aim of this study is to examine whether glycocalyx volume, as estimated by SDF-imaging, is associated with cardiovascular risk as estimated by conventional risk scores.
The aim of this study is to compare the 16S PCR technique with standard bacterial cultures of infected vascular grafts, mycotic aneurysms and non-infected aortic aneurysms.
To describe the differences in macrophage infiltration and mRNA expression of adipocytokines in subcutaneous, omental and perirenal fat tissue in Cushing's syndrome compared to healthy controls.
To identify some of the mechanisms in patients in remission of Cushing*s syndrome that contribute to the persistence of visceral obesity, systemic inflammation, insulin resistance, sarcopenia, a low muscle oxidative capacity and increased risk of…
Are AGEs, as a predictor of increased risk for cardiometabolic syndrome, increased in shift workers?
The aim of this study is to investigate skin AGEs, as a predictor of increased risk for cardiometabolic syndrome, in a shift work population as compared to non-shift workers to assess its potential as an early assessment of the actual risk for…
Effect of SCS on CBF
Our overall objective is to better understand the role of regulatory B cells in disease pathogenesis and to better predict disease flares in order to individualize treatment.
1. To assess neuroimaging hallmarks of RVCL disease stages;2. To evaluate cerebrovascular reactivity as a biomarker of endothelial (dys)function in RVCL patients, in migraine patients and healthy controls;3. To identify shared pathophysiological…
The objective of this pilot study is to provide information about the usefulness of NIRS in the study of patients with JDM in the test configuration as described in the protocol. For this purpose, the microvascular oxygenation and hemodynamics in…
We hypothesize, that during an oral glucose tolerance test, the OPS arterial flow measured sublingual will be comparable within the same subject, but different between young, elderly and type 2 diabetic patients. Objective is to quantify differences…
This study concerns a research that is aimed to investigate the prevalence of the metabolic syndrome in a group of patients known with ANCA-associated vaculitis. Hereby we will compare the presence of the metabolic syndrome between an ANCA-…
What is the base-line StO2 reference value in intestinal stoma's. ? Is NIRS a reliable detector of intestinal ischamia ? What is the influence of filling-status on StO2 in the stoma and sublingually ? What is the influence of NTG on StO2 in the…
The main objective of this study is to show that the basilic vein transposition in the current elderly population is superior to the brachiocubiti fistula in terms of easy cannulation and maturation. Primary outcome is one year patency We will also…
In this study the effects of a two-week moderately intense-intense physical activity on vascular function, glucose-metabolism, lipid-metabolism and adipose tissue function will be analyzed.
Quantifying the level of exposure to air pollutants during commuting by car, bus and bicycle. And characterizing the health effects caused by short-term exposure to traffic-related air pollution.
Primary objectives1. To investigate prospectively the prevalence of cardiovascular damage due to cancer treatment and it*s change over time.2. To investigate markers of early and late toxicity of cardiovascular damage due to cardiotoxic treatment.…
Our working hypothesis is based on the interplay between vascular dysregulation, neuropathological alterations and decline in AD brain function. In the latent phase vascular dysregulation is already apparent when patients are asymptomatic.…