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Effect of infrapatellar nerve block on chronic anterior knee pain after tibial nailing.

To study the effect of a nerve block of the infrapatellar nerve with local infiltration with lidocaine or saline on chronic anterior knee pain after tibial nailing.Secondairy objectives:- to measure knee pain on a VAS for eight different activities…

The BALANCED Anaesthesia Study: A prospective, randomised clinical trial of two levels of anaesthetic depth on patient outcome after major surgery

We are performing a large randomised trial of *deep* versus *light* anaesthesia to definitively answer the question of whether anaesthetic depth alters perioperative outcome. Elderly patients undergoing major surgery will be randomised to an…

A clinical study to investigate the effects of remote ischemic preconditioning on cardiac mitochondrial hexokinase in CABG patients

The aim of this clinical study is to investigate whether RIPC induced cardioprotection is associated with an increased amount of mitochondrial HK (mtHK) in the heart.

The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Patient

Our primary objective is the effect of taurine on morbidity and consequent mortality.

Pilot-investigation: The reduction of embolic and there by neurologic complications after cardiac surgery by the use of a non-invasive imaging technique(CABG, on pump)

This pilot is meaned to obtain:- experience and understanding in the presence of new embolic load in the brain by means of DW-MRI- Understanding in the number of patients in which probably the post-operative DW-MRI can not be done according to…

Paradoxical and venous Gas Embolism During Hysteroscopic Surgery Detected by Trans Esophageal Echocardiography: A comparison using either bipolar or monopolar diathermia

To determine the incidence and grade of venous emboli and/or paradoxical gas emboli during hysteroscopy surgery using TOE. In addition, a comparison will be made using either bipolar or monopolar diathermia. Knowing the incidence and severity of…

Mesenteric Sparing versus more extended mesenterectomy in Ileocolic Resection for ileocecal Crohn*s Disease

With this study, we hope to decrease recurrent Crohn*s disease.

The Rotterdam Antiplatelet Therapy in Vascular Patients Study

The objective of the proposed study is to evaluate if results as are written above, are to be extrapolated on high risk patients who underwent vascular surgery. In this group of patients, there is a substantial risk of 15-20% to die in the first…