Search for a trial

Effect of a Platelet Rich Plasma (PRP) injection on the outcome of chronic lateral epicondylitis.
A double blinded randomized controlled clinical trial.

The effectiveness of PRP treatment in patients suffering from chronic lateral epicondylitis is still ambiguous. Therefore we study PRP treatment in a double blind randomized controlled trial in a homogeny patient population with respect to duration…

The treatment of moderate to severe onychocryptosis with either a wedge resection with or without phenolization or partial nailmatrix resection with phenolization, a randomized controled trial.

The objectification of the most effective surgical treatment, in which three operationprocedures are compared.

Wireless Micro Current Stimulation: adjunctive therapy for acute and chronic wounds * a randomized controlled trial.

Our aim is to determine whether Wireless Micro Current Stimulation accelerates wound healing in chronic wounds as well as surgical wounds healing by secondary intention, as compared to standard treatment. Furthermore, by usage evaluation we intend…

Biomarkers for soft tissue damage in a rigid and a soft-layered spineboard

In this study we want to investigate if there are differences in cytokine and mFABp production when using a rigid and a soft-layered spineboard, in relation to tissue-interface pressures. Furthermore, redness of the skin and experienced comfort are…

Within-patient comparison of Senti-Scint and ICG-99mTc-nanocolloid for sentinel node biopsy of melanoma of the head and neck, of the trunk or of an extremity

To compare ICG-99Tc-nanocolloid to 99mTc-Senti-Scint for sentinel node mapping in patients with malignant melanoma of the trunk, an extremity or in the head and neck area.

A Multicenter, Prospective, Single-Blind, Randomized, Controlled, Study of the Repair of Challenging Abdominal Wall Defects: Strattice TM in abdominal Wall Repair (StaR)

The primary objective of this clinical study is to compare the incidence of post-repair wound related complications, including hernia occurence/reccurence between challenging abdominal wall defects repaired with Strattice Reconstructive Tissue…

Clinical Application of a Dermal Substitute based on glycerol
preserved Allograft: GLYADERM®
A multicentre, prospective, controlled, randomized, comparative
trial of Glyaderm® and split thickness skin graft versus split
thickness skin graft alone in full thickness skin defects

Objective: The main objective is to evaluate the difference in scar quality, after skin restoration of full thickness defects treated with Glyaderm® and STSG versus STSG alone.Secondary objectives are: to evaluate the percentage of Glyaderm® take…

Treatment of surgical scars in breast reduction with laser device, to prevent scar hypertrophy.

There are indications that early laser treatment of wounds can reduce scar formation. With the laser device the wound will be heated, which is thought to be responsible for a reduced inflammatory reaction and hence for a reduced scar formation. The…

A phase II study of ARA 290 as therapeutic strategy in no-option critical limb ischemia patients.

A proof of concept study to test whether ARA 290 improves wound healing and reduces neuropathic pain in no-option patients with CLI

A pilot randomized controlled trial comparing the effect of a percutaneous and lipofilling technique in patients with a secondary Dupuytren*s contracture with standard fasciectomy surgery on convalenscence, contracture correction and recurrence rate.

To compare treatment of secondary Dupuytren*s contracture by standard limited (dermo)fasciectomy and by the modified percutaneous release combined with fat grafting. We focus specifically on return to function and if applicable to return to work (…

Treatment of subcutaneous abdominal wound healing impairment after surgery without fascial dehiscence by Vacuum-Assisted Closure® (V.A.C. ® SAWHI-Study) versus standard conventional wound therapy

The primary objective of this multicenter, parallel design, prospective, randomized clinical trial, with repeated observations over time, is to compare the clinical, safety, and economic outcomes of V.A.C.® Therapy and SCWT based on an open…

The effects of Suprathel® versus a calcium alginate on pain perception and comfort in split-thickness skin graft donorsites.

The primary objective of this research is to compare pain experience and comfort when a calcium alginate or Suprathel® is used on the donor site. Secondary objectives are the differences in scarring, itching of the scar tissue and costs involved…

Biomarker Expression, predicts risk of re-AMputation, impaired woundhealing and secundairy systemic cardiovascualr events, in patients with endstage peripheral atherosclerotic disease undergoing leg amputation due to advanced atherosclerotic disease. The "BEAM" study.

The objective of the study comprises the identification of (tissue) biomarkers related to the risk of re-amputaion, systemic atehrosclerotic manifestations and woundhealing in patients with critical limb ischemia by investigating tissue biopts at…

Male Infertility After Totally ExtraPeritoneal Hernia Repair (TEP)

The primary aim of this study is to examine/determine the effect of Totally ExtraPeritoneal (TEP) endoscopic hernia repair on male fertility. To measure this outcome, we examine testicular perfusion, volume, semen quality and blood levels of…

Wound treatment in orthopedic surgery; a prospective randomised study of Aquacel Surgical versus Curapor after total knee and total hip surgey.

This research aims to conduct blistering and reduce freguent dressing changes in patients undergoing total hip replacement or total knee replacement have undergone in the use of Aquacel Surgical dressing.This compares with the usual method of wound…

A prospective, randomized, intra-patient, comparative, open, multi-centre study to evaluate the efficacy of a Single-Use Negative Pressure Wound Therapy (NPWT) System (PICO) on the prevention of postsurgical incision healing complications in patients undergoing reduction mammoplasty

Primary Objective:To assess the difference in healing complications up to and 21 days post-operatively between postsurgical incisions treated with PICO compared with standard of care Incision healing complications will include;* Skin necrosis*…

A Randomized, Controlled Study to Evaluate the Safety and Effectiveness of EVICEL* as an Adjunct to Sutured Dural Repair

To evaluate the safety and efficacy of EVICEL for use as an adjunct to dura sutures in elective cranial surgery to provide intraoperative watertight closure.

Efficacy of Arnica D1 ointment after upper blepharoplasty: a randomized, double-blind, placebo-controlled study

To evaluate the efficacy of Arnica om postoperative outcome after upper blepharoplasty.

In vivo identification of peripheral nerve bundles during surgery using optical spectroscopy techniques: a pilot study

With this pilot study we aim to prove that our optical spectroscopy system can provide accurate identification of nerve tissue during surgery.

Sensibility of the upper eyelid after blepharoplasty

The objective of this study is to find the prevalence and type of sensibility problems after upper blepharoplasty. Also we will study the postoperative course of possible problems in sensibility.