100 results
To assess long-term scar quality of deep/sub dermal (burn) wounds after skin grafting with micrografting technique compared to meshed grafting technique.
This study has been transitioned to CTIS with ID 2024-511743-26-00 check the CTIS register for the current data. Primary Objective: Major amputation rate after 12-months of follow-upSecondary Objectives: - Amputation-free survival- Health-related…
Primary objectivesTime needed for proper closure of the trocar wounds with the automated deviceSecondary objectivesDemonstrate user-friendliness of the Mediclose System
To assess the change in scar pliability measured by the Cutometer (primary outcome) pre- and 12 months post grafting and to quantify clinical and histological improvements of scar characteristics with the combination therapy of SVF enriched fat…
To collect safety and efficacy data from study participants that have been treated with the miraDry System using High Volume Anesthesia (HVA, also known as LTA or Local Tumescent Anesthesia) method as the local anesthesia delivery method.
The high morbidity rate of the perineal wound has resulted in a continuing discussion on how to close the perineal defect after APR. Our research group recently published the BIOPEX-study (NL42094.018.12), in which 104 patients were randomized…
Primary Objective: Primary objective of this trial will be to determine whether iNPWT reduces the number of patients with clinically relevant* SSOs after (potentially) contaminated ventral hernia repair <30 days after surgery. *A SSO is…
To study the most relevant outcome measures and a cost-effectiveness analysis of laparoscopic PIRS technique compared to open hernia repair in infants aged 6 months to 16 years of age with a primary unilateral inguinal hernia
Primary Objective:The primary objective is to assess the efficacy of LVA surgery in comparison to sham procedure in patients with cancer related lymphedema in the context of improvement of Lymph-ICF score at 12 and 24 months follow up. Secondary…
This pilot study assesses the performance of a robot-assisted microsurgery. Lympho-venular anastomosis(LVA) is the most difficult procedure in microsurgery at this moment. This LVA technique is applied to treat for example breast cancer related…
: To investigate whether the omission of surgical gowns during CTR and TVR surgeries af-fects postoperative wound infections
This study aims to demonstrate that the new generation of the HAPI, the Wireless Perfusion Imager (WIPI) is able to visualise the microcirculation of the abdominal flap and the newly reconstructed breast during DIEP flap breast reconstruction. The…
To assess whether the use of Virtual Reality Therapy can reduce pain, and anxiety than without Virtual Reality Therapy in patients undergoing complex wound care procedures.
Primary- Does the application of Virtual Reality (VR) reduce anxiety in patients undergoing treatment for traumatic injury in the emergency department compared to patients not using VR headset? Secondary- Does the use of Virtual Reality (VR) lead to…
The main objectives of this study are to investigate to what extent:1) VRT and MT can contribute to pain reduction compared to patients who receive no VRT and MT intervention during complex wound care; and2) VRT can contribute to pain reduction…
Primary objective: Investigation of mean peak plantar pressure at the location of the diabetic foot ulcer and at 6 plantar regions of the foot (i.e. hallux, digits, first metatarsal, second to fifth metatarsals, midfoot, and heel) during total…
With this pilot study we aim to determine the feasibility and efficacy of the novel catheter set, the Semiflex Dome Catheter System, for vacuum therapy of perianal abscesses/sinuses and fistulas. The pilot study will consist of 2 parts. First, 10…
This study will determine whether there is a difference in disease free survival for patients treated with either a 1cm excision margin or 2cm margin for clinical stage II (pT2b-pT4b) primary cutaneous melanoma (AJCC 8th edition, Table 1). The study…
This study has been transitioned to CTIS with ID 2023-508530-34-00 check the CTIS register for the current data. Primary objective:* To demonstrate the efficacy of alpelisib as measured by the proportion of participants randomized to alpelisib with…
We do not currently have enough knowledge about the potentially beneficial effect that hyaluronidase might have on skin flap angiogenesis.