49 results
Primary objective: to investigate the prevalence of vestibulotoxicity and disturbance of equilibrium as far a Cystic Fibrosis patients with at least one treatment with tobramycin are concerned. Secondary objective: To formulate an advice for…
The main objective is to demonstrate the activation of the efferent inhibitory cortico-olivocochlear pathway with otoacoustic emission of the ear contralateral to the side of stimulation with TMS. We expect the amplitude to decrease after TMS of the…
The primary objective of this study is to objectivate neural hyperactivity at the cortical level of chronic tinnitus sufferers compared to control subjects with the use of FDG-PET-scans.
1. To implant a functional vestibular prosthesis using the ampullar *V*-approach, as developed in our own clinic.2. To investigate protocols for adjusting the vestibular implant (VI) to required settings, regarding:-- Modulation sensitivity--…
In this study we want to investigate the clinical and cost-effectiveness of internet-based VR, with and without physiotherapeutic support, for older dizzy patients in general practice in comparison with usual care. Furthermore, we want to identify…
The primary objective is to clarify the frequency of t-BPPV in patients after mild TBI. Secondary objectives are: assessment of the symptoms of t-BPPV and the treatment success of t-BPPV.
The main objective of the study is to better explain disappointing speech recognition in individual cases, with as ultimate goal to find optimal individual settings for the sound processor (outside the scope of this project). We test two new methods…
To determine the sensitivity and specificity of the HINTS+ test in detecting a central cause in patients with acute onset, continuous dizziness in a general ED population, when performed by general neurologists/ED physicians.
The aim of this study is to measure eCAPs intraoperatively (and perform electrocochleography [ECochG] in case of any residual hearing) and to estimate cochlear health in these patients by applying insights gained from our guinea pig experiments.
To evaluate the vestibular function relating results to surgery, radiotherapy, active surveillance, intratympanic gentamicin, and intratympanic gentamicin followed by active treatment based on objective vestibular testing and dizziness related QoL.
The primary objective is to investigate the course of limitations in physical activity and daily functioning in patients who are diagnosed with unilateral or bilateral vestibular hypofunction, and to identify factors that are associated with this…
This study has been transitioned to CTIS with ID 2024-512860-75-00 check the CTIS register for the current data. The aim of this feasibility study is to validate pre-treatment [89Zr]-bevacizumab PET/CT as an imaging biomarker for prediction of…
The primary objective of the VertiGO! trial is to assess the feasibility of restoring vestibular function by making use of prolonged VI stimulation. This will be done using a combined VI and CI device: The CVI. To achieve this objective, patients…
The aim of this study is to investigate whether the type of surgical approach to the cochlea; CO or eRW using the Nucleus 632 with the Slim Modiolar electrode affects the final residual hearing and secondarily, intracochlear trauma and electrode…
Primary aimTo determine the prevalence of children with hearing loss at time of discontinuation of cancer therapy in a prospective full cohort of 600 children with solid and CNS tumors.The secondary objectives of this study are:- To study the…
1. Monitoring of auditory function during destructive labyrinth surgery to study hearing preservation and vestibular implantation2. Monitoring of vestibular function during destructive labyrinth surgery to study better electrode position and…
Primary Objectives: • To evaluate the subjective and objective cognitive complaints and cognitive function in patients receiving radiotherapy for their vestibular schwannoma. Secondary objectives:• To explore the use of (MRI) imaging biomarkers for…
This study assesses whether EDB surgery will result in a significant reduction in the number of patients without vertigo spells at 12 months follow up, compared to patients who undergo endolymphatic sac decompression.
The primary objective is to study the impact of continuous vibrotactile feedback during waking hours in daily life on balance, (fear of) falling, fatigue, and overall functioning. The secondary objective is to study the impact of a vibrotactile…
To study the human adult cochlea, in specific it*s RNA and protein expression patterns and morphology.