Search for a trial

The influence of mannose-binding lectin (MBL) on the course of disease in patients with cystic fibrosis (CF).

1. To study the possible association between MBL-deficiency and the occurence and severity of infections in MBL-deficient CF patients.2. To study the possible association between MBL-deficiency and the severity of cystic fibrosis.3. To study the…

The influence of chloroquine-dosage as comedication on the response of "non-responder" dialysispatients at Hepatitis B vaccine

Study whether chloroquine as comedication results in a better respons on Hepatitis B vaccination in non-responder dialysis patients.

A Phase I, open label, randomized, crossover trial in healthy subjects to investigate the pharmacokinetic interaction between didanosine and TMC114, coadministered with low-dose ritonavir, at steady-state.

The primary objectives are:* to determine the effect of steady-state concentrations of TMC114 coadministered with a lowdose of ritonavir on the steady-state pharmacokinetics of ddI,* to determine the effect of steady-state concentrations of ddI on…