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Game Ready continuous-flow cryo- and cyclic compression therapy after fracture treament of the hip: a prospective multicenter, open-label, multicenter, randomized, controlled, clinical trial on postoperative effects on pain.

The goal of the study is whether to establish if application of combined cyrocompression therapy directly postoperative after hip fracture surgery results in a significant reduction in painperception en whether this reduces the morfine consumption.…

Remifentanil use for procedural sedation and analgesia in the emergency department

Answering the following questions:1. Main question: Is remifentanil a usefull medication for PSA in the emergency department?2. What is the recovery time of the patient when using fentanyl / propofol / remifentanil (time between last gift PSA…

*Does maintaining endotracheal tube cuff pressures at 20 mm Hg prevent dysphagia and hoarseness after anterior cervical spine surgery?*
A randomised controlled trial.

To determine if adjusting endotracheal tube cuff pressure after placement of a retractor during anterior cervical spine surgery prevents postoperative dysphagia. Furthermore laryngo-tracheal complaints (hoarseness and sore throat) will be scored.

Decongestants for dilating the nasal cavity, a randomised, blinded, prospective study to prevent iatrogenic epistaxis during nasotracheal intubation

Primary Objective:The purpose of this study is to investigate the clinical efficacy of xylomethazoline, combined with dilating the nasal passage way with a polyvinyl-alcohol nasal dilator in the prevention of iatrogenic epistaxis during nasotracheal…

Patient Opinions of Screening for Intimate Partner Violence

Primary Objective: Our primary objective is to determine if it is acceptable to patients in the trauma clinic for orthopaedic/trauma surgeons, orthopaedic/trauma nurses, and/or social workers in the trauma clinic to screen for IPV.Secondary…

Pressure and tissue deformation while using a regular and a newly developed soft-layered long spineboard.

The primary objective of this study is to evaluate if there are differences in the tissue-interface pressures, pressures inside the tissues and tissue deformation in the sacral area when volunteers lie on a regular spineboard versus a vacuum…

Evaluation of a newly developed spineboard in anaesthetized patients.

We want to study whether there is a difference with respect to the pressure exerted onto the body when using a normal spineboard and a newly developed spineboard, related to the level of consciousness of the volunteer. Also the experienced comfort…

Does Misoprostol facilitate insertion of an Intra Uterine Device (IUD), both copper-containing as well as levonorgestrel-releasing, among nulli- and multipara?

To investigate whether Misoprostol (compared to placebo) will diminish the amount of insertion failures. To investigate whether Misoprostol (compared to placebo) will diminish the amount of insertion related complications (eg. syncope, perforation…

Complications in ankle arthroscopy

To asses the percentage of permanent complications after ankle arthroscopy, and to assess the type of complications and the procedures after which the complications occur.

The development and examination of an intervention aimed at youths who have to be treated at the emergency department of a hospital as a result of excessive alcohol use.

Aim of the study is to develop and test a brief intervention for adolescents who have to be treated in the emergency department of a hospital due to excessive alcohol use.

The effectiveness and cost-effectiveness of a proprioceptive balance board training programme for the prevention of recurrent acute lateral ankle sprains; a randomised control trial.

The proposed study evaluates the effect of a proprioceptive balance board training programme on ankle sprain recurrences that is applied to individual athletes after rehabilitation and treatment by usual care.

Pressure and Silicone treatment in Hypertrophic Scarring

The objective of our observational clinical trial is to quantify the apoptosisrates of fibroblasts and growth-factorchanges in hypertrophic (burn) scars treated with pressure and/or silicone therapy.

Correction of Sub-clinical Prolongation of COAGulation Tests and/or Low Platelets before TRACHeotomy
- Randomized controlled trial *

To determine if patients with sub-clinical lengthening of coagulation test, low platelets or use of Ascal have increased risk of clinical significant bleeding during and after tracheotomy.

Primary Closure of the lower limb and chest wound with Steri strip S in comparison with inter-cutane sutures in patients undergoing CABG.

To investigate whether application of Steri-Strip* S will lead to: 1) shorter treating time 2) improved satisfaction with the patient 3) improved wound healing4) improved cost-efficiency5) improved satisfaction with the attendant

Anticoagulant treatment after knee arthroscopy or during plaster cast lower leg immobilisation: determining the balance between benefits and risks

Comparative effectiveness research to determine cost-effectiveness of an existing healthcare policy, i.e. treatment with low molecular weight heparin (LMWH) after knee arthroscopy and lower leg plaster cast immobilization following surgical or…

Effect of postoperative negative pressure wound therapy (Prevena TM) in clean closed surgical incisions on the incidence of wound dehiscence in low and high risk patients: a rondomized controlled pilotstudy.

The aim of this study is to compare the effect of a postoperativenegative pressure dressing (Prevena (TM) IMS) with a standardwound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in low riks and high…

Effect of a negative pressure dressing (Prevena TM) on the prevention of wound dehiscence in clean closed surgical incisions: a rondomized controlled trial.

The aim of this study is to compare the effectiveness of a negative pressure dressing (Prevena (TM) IMS) with a standard wound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in patients, undergoing an…

Gauze throat at Oropharyngeal surgery

To investigate postoperative nausea and vomting in patients with or without a gauze throat after an operation of the mouth

Time-effectiveness of Mini-C-arm FLuoroscopy ASsisted Closed Reduction of Distal Radius Fractures versus Standard RadiograpH: The FLASH-trial, a randomized controlled trial

The aim of the current study is to assess the potential time- and cost-savings of fluoroscopically aided reductions of dislocated DRFs in adult patients.

LIMB-Q: Validation and field testing

The purpose of this study is to complete the third and final phase of PRO instrumentdevelopment, cross-sectional field-testing of the LIMB-Q. The field-test data will be analyzedto identify the subsets of items for each scale that represent the best…