37 results
To evaluate anti-tumor activity of T-cells in the GALT of patients with PDAC.
To investigate safety and tolerability as well as the induced immune response upon MesoPher/mitazalimab combination therapy in metastasized pancreatic disease after (modified) FOLFIRINOX.
Investigate whether perioperative mFOLFIRINOX improves overall survival compared to adjuvant mFOLFIRINOX in resectable pancreatic cancer.
This study has been transitioned to CTIS with ID 2023-505220-57-03 check the CTIS register for the current data. The PLANCTON trial will investigate the effect of early intravenous OM-3 FAs on new onset organ failure and mortality in patients with…
This phase I/II study consists of 2 subsequent study parts. In the phase I part we will investigate the safety of combining IMM-101 administration with SBRT in 20 patients with locally advanced pancreatic cancer who have completed at least 4 cycles…
Investigate whether the use of the Hot AXIOS lumen apposing metal stent is superior to standard plastic pigtails stents for drainage of infected pancreatic necrosis.
The objective of this study is to compare the efficacy of chemotherapy and IRE (experimental arm) to the efficacy of chemotherapy and radiation (control arm) in patients with locally advanced, non-resectable, non-metastasized, pancreatic cancer.
This study has been transitioned to CTIS with ID 2024-514598-23-00 check the CTIS register for the current data. This is an open-label, non-randomized, multicentre phase II study with an initial safety-run in. During the safety run-in phase, we will…
This study has been transitioned to CTIS with ID 2024-514597-42-00 check the CTIS register for the current data. The primary objective of the safety run-in (phase Ib) is to determine the safety of combination therapy with durvalumab and rintatolimod…
This study has been transitioned to CTIS with ID 2024-518627-29-00 check the CTIS register for the current data. PRIMARY OBJECTIVE• To compare the efficacy of Ampligen® versus control group / no treatment following FOLFIRINOX in subjects with…
To validate and assess the impact of the use of the MyCyFAPP system for self-management in children with CF, more specifically the effect on patients* quality of life, nutritional status, gastro-intestinal symptoms, general wellbeing and economic…
Determine whether micellar curcumin (Espera®) is able to improve the Systemic Immune Inflammation index in operable PDAC patients OR (metastasized) pancreatic cancer patients with stable disease after standard of care treatment.
The aim of this research is to investigate whether it is feasible and safe to treat operated pancreatic cancer patients who have completed standard of care treatment with dendritic cell immunotherapy using dendritic cells loaded with autologous…
Primary objectiveTo investigate whether the addition of preoperative radiochemotherapy to the standard treatment, consisting of explorative laparotomy, pancraticoduodenectomy if possible, followed by adjuvant chemotherapy, improves the overall…
It is a two-step approach study: The main objective in the first approach is to obtain a mathematical predictive model (MPM) adapted to each patient*s gastrointestinal conditions that calculates the optimal amount of enzymatic supplements for the…
Determine the efficacy and safety (using objective response rate) of tremelimumab in patients with advanced solid tumors (UBC, PDAC, TNBC).
The objective of this study is to prospectively document the performance of a fully covered self expanding metal stents (FCSEMS) for treatment of pancreatic duct strictures in patients with painful chronic pancreatitis.