19 results
To identify the pathophysiology and predictors of study (extreme) cancer treatment -induced cardiovascular toxicity in cancer patients, by in vitro investigation of cardiovascular toxicity in patient-derived cardiomyocytes (iPSC-CMs) and endothelial…
The objective of this study is to Identify relevant geriatric instruments and compose a clinical model to predict tolerance and toxicity in elderly cancer patients who are treated with chemotherapy for their (metastasized) malignancy.
To assess the preemptive effect of Bepanthen® on decreasing the incidence of specific >= grade 2 dermatological side effects of interest in respect of compliance to EGFRI agents, HRQoL and the adherence during the 6-week skin treatment period…
To preserve testicular tissue of young boys with cancer for possible autologous transplantation in the future if infertility has become apparent.
To develop and evaluate the OncoActive+ project that aims to increase the amount of physical activity of (former) cancer patients. The main goal of this study is to test the effect of the intervention on physical activity behavior, as well as the…
To evaluate the effect of chemotherapy on the serological and cellular immune response to influenza virus vaccination in patients with breast or colorectal cancer in order to establisch the optimal timing of vaccination during treatment with…
To investigate the optimal timepoint of replanning during a curative radio(chemo)therapy in patients with Head and Neck cancer. Furthermore we like to analyze if the optimal timepoint of replanning is depending on tumorlocation, tumor volume or…
1: Elucidation of the factors that cause the complement deficiency in pediatric oncology patients. First, we will characterize the inhibitor of MASP-2 activity in patients during chemotherapy. 2: Identification of the complement component(s) causing…
Fertility follow-up of the women who visited our out patient ward for information on fertility preservation before starting gonadotoxic treatment
reduction of fluid administration of 30%
The first objective is to assess which determinants predict swallowing dysfunction after curative (chemo)radiation. We want to determine the possible relationships between the radiation dose distributions in anatomical structures involved in…
Primary Objective: To assess the effect of esomeprazole on the pharmacokinetics of BMS-275183. Secondary Objectives: To evaluate the safety and efficay of BMS-275183 co-administered with esomeprazole.
Primary: to investigate the effectiveness of using Hospital Fit as part of the physiotherapy treatment on average time spent walking per day in patients hospitalised at the Medical Oncology or Cardiology Departments of the Maastricht University…
To determine wheter the use of the taurolidine 1.35%, citrate 4%, and heparin 100 IU/ml lock solution (TauroLock*-Hep100) reduces the incidence of first tunneled central line associated bloodstream inections (CLABSI) compared to the heparin 100 IU/…
The main objective of this study is to examine the effect of motivational coaching following oncological rehabilitation in cancer patients, on minutes of moderate- to- vigorous physical activity (MVPA) measured after six months, with an…
This randomized phase II open label study examines the effect of controlled cooling versus no cooling on the incidence and severity of oxaliplatin-induced peripheral neuropathy (OIPN) in patients treated with oxaliplatin.
The overarching objective of this master protocol is to study the risk factors (personal, clinical and lifestyle factors) for-, and consequences of- , changes of nutritional status (both over- and undernutrition) in children with cancer. Based on…
PRIMARY OBJECTIVE: -To assess the antibody response after mRNA (Pfizer, Moderna) SARS-CoV-2 vaccination in children with cancerSECONDARY OBJECTIVES:To assess in children with cancer after SARS-CoV 2 vaccination:- durability of the antibody response…
The primary objective of this study is to proof the concept that cisplatin-induced ototoxicity can be prevented by transtympanic STS containing gel application, through inserted grommets.The STS containing and blank gel formulations will be provided…