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MOSAIC-2 Study: MOdel to Study upper Airway Immunity upon Cholera vaccination

To investigate whether raw milk, pasteurized milk or ultra-heat treated (UHT) milk is able to enhance the systemic immune response as induced by oral cholera vaccination, in comparison to regular vaccination. Oral vaccination can also induce an…

The Orange III trial: Optimised recovery with Movicol preoperatively within an enhanced recovery programme, a randomised controlled trial

The aim of this study is to accelerate recovery after liver surgery by enhancing intestinal passage through the preoperative use of Movicol®.

Retrograde in situ hypothermic perfusion of the liver during right hemihepatectomy

To reduce intraoperative blood loss and enhance tolerance of the FRL to I/R injury during right hemihepatectomy under vascular exclusion by means of in situ hypothermic perfusion with retrograde outflow (R-IHP) of the FRL.

Antecolic versus retrocolic route of the gastroenteric anastomosis after pancreatoduodenectomy: ARCO-trial

Primary objective:To determine the relationship of route of gastroenteric anastomosis after PD and postoperative incidence of DGE.Secondary objectives:To determine the relationship of route of gastroenteric anastomosis after PD and gastric emptying…

Consequences of liver surgery for liver function and cell injury

1 Primary Objective To investigate the effects of 15* liver ischemia versus 30* liver ischemia on liver injury and liver function.To investigate the effect of liver manipulation during mobilisation for a right hemihepatectomy, that can be used as a…

Wountherapy in patienten with a sinus pilonidalis using a VAC-therapie versus Kerlix-gauze.

To show the differrence of total healing of wound between two therapies, VAC and gauze-therapy, in patient with a sinu pilonidalis after chirgical intervention.

The application of autologous platelet rich fibrin reduces allogeneic blood transfusions and improves wound healing in total hip arthroplasty

The primary objective of this study is to investigate whether application of PRF® will reduce postoperative wound leakage, the necessity for allogeneic blood transfusions and the incidence of wound healing disturbances in patients undergoing…

Insertion of a central venous catheter through a tegaderm as a preventive measure against catheter colonization and infection

Primary: Investigate if sterile transparent dressing pasted on the skin before CVC insertion reduces the contamination risk of the CVC.Secondary: Investigate if direct contamination has a clinical significance.Investigate what the mayor…

World-Wide Randomized Antibiotic Envelope Infection Prevention Trial

The primary study objective is to compare the rate of major CIED infections through 12-months post-implant between the TYRX envelope group and the control group.

Right Dose, Right Now: Randomized Controlled Clinical Trial

To assess the influence of dosing guided by AutoK on achieving PK targets and clinical endpoints in intensive care patients with sepsis.

ERCP brush cytology of pancreatobiliary strictures - Infinity versus Boston Scientific RX cytology brush: a randomized controlled trial

To compare the sensitivity of ERCP brush cytology between standard RX cytology brush and Inifinity brush in patients with pancreatobiliary strictures suspicious for malignancy.