210 results
The objective of the study is to evaluate the efficacy and safety of a single sub-retinal injection of AAV2-REP1 in subjects with choroideremia (CHM).
The aim of this study is to validate a recently created online refraction method by comparing the outcomes of the online refraction method with the *golden standard* manifest refraction.
The first goal of the PLING-project is to improve the clinical applicability of the training by developing a home-based app that can be on any Windows or Mac system. The second goal is to optimize training gain by: 1) increasing the number of…
In this study, we want to demonstrate that MPP is no less effective than MPP plus XRT.
The new drug delivery device is a rod-shaped metal bar, called an ocular coil. The coil can be loaded with one (or more) drug(s) en can be placed easily in the lower eyelid of the eye. In this way, the drug can be released to the eye in a constant…
To determine whether corneal clearance is obtained with endothelial transplants of smaller size and/or lower endothelial cell counts.
Objectives in adult patientsPrimary Objective:To demonstrate the efficacy of Holoclar® at one year after the first treatment in patients suffering from moderate (vascularization in two-three corneal quadrants with central corneal involvement) to…
To evaluate the effectiveness and costs of immediately sequential bilateral cataract surgery (ISBCS) compared to delayed sequential bilateral cataract surgery (DSBCS; usual care) in order to determine whether ISBCS is an effective and cost-effective…
The aim of this research is to find out which lens gives the best results.
Primary Objective:To demonstrate the long term safety of one or two ACLSCT(s) in patients suffering from moderate to severe LSCD secondary to ocular burns. Secondary Objectives:• To evaluate the long-term efficacy of one or two ACLSCT(s), the degree…
To show in a prospective randomised study if intravitreal injection of Triamcinolonacetonide combined with Macula Grid Laser gives a better increase in visual acuity and/or decrease in macular edema than Macula Grid Laser combined with sub-Tenon…
The aim of this study is to compare the 3D designed prosthesis with the conventional made prosthesis.Study questions:- How is the 3D designed prosthesis compared to the conventional prosthesis? The final chosen workflow and settings will be applied…
To determine the outcome in CSR patients comparing treatment with PDT versus observation.
The goal of the trial is to compare the efficacy and costs of bevacizumab 1.25 mg and ranibizumab 0.5mg given as monthly intravitreal injections over 6 months for the treatment of diabetic macular edema.
To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of 2 dose strengths of Bimatoprost SR in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) after initial and repeated administrations
Development of a method and diagnostic instrumentation for characterizing the peripheral ocular characteristics of normal subjects (with healthy eyes) in a clinical setting.Primary objective of the study: To measure the distribution of the ocular…
To determine whether corneal clearance of FED eyes within the first 6 months after the procedure is obtained by using *descemetorhexis only* after removal of DM, guttae and/or the affected endothelium.
Primary:• To demonstrate that RTH258 6 mg is not inferior to aflibercept 2 mg with respect to the change in best-corrected visual acuity (BCVA) from Baseline to Week 48Secondary:• To demonstrate that RTH258 6 mg is not inferior to aflibercept 2 mg…
Primary Objective:The primary objective of this study is to demonstrate the long-term (3 years) favorable visual acuity and adverse event outcomes for the Clareon IOL compared to historical SPE rates as reported in EN ISO 11979-7:2014.Secondary…
The primary objective of this study is to evaluate the long-term safety and tolerability of ITV injections of 10 mg lampalizumab administered to patients with GA secondary to AMD as assessed by the:• Incidence and severity of ocular adverse events•…