18 results
The primary objective is to show a difference in responder rates between the study product (T4020) and the vehicle : a reduction of 50% or more in keratitis/ulcer area from baseline (inclusion visit = V2 = Day 0) assessed at Day 28 (Visit 6).
To simplify the operational technique for the eye surgeon. To minimize the risk of complications which occur occasionally with the standard technique, such as glaucoma and cataract. In addition, the surgery is less burdensome to the patient since…
The primary objective is the degree of IOP lowering after trabeculectomy with adjuvant Ologen® implantation, in comparison to trabeculectomy with mitomycin-C. Secondary objectives are peroperative and postoperative complications, and postoperative…
Primary ObjectiveTo investigate whether half-dose PDT treatment leads to a higher percentage of chronic CSC patients with subretinal fluid on OCT achieving an absence of this subretinal fluid on OCT as compared to HSML treatment.Secondary…
Primary: To demonstrate that intravitreal injection of 0.5 mg ranibizumab administered based on individual patient needs has superior efficacy compared to sham treatment in adult patients with visual impairment due to VEGF-driven ME. Secondary: Best…
The goal of this study is the development of a clinically verified functional imaging technique of the retina.
To examine features of treatment response on optical coherence tomography in patients who were switched to aflibercept after non-response to previous intravitreal anti-VEGF treatment.
To demonstrate that externally induced increases in epipalpebral pressure (EPP) relate to clinically significant increases in IOP, and to determine posture dependency of EPP. To determine the effects of protective goggles on EPP under these…
The purpose of this study is to collect and complement long-term clinical follow-up data from patients and families with choroideremia. We hope to increase our understanding of the clinical course of choroideremia.
The primary objective of this study is to demonstrate that the IOP-lowering efficacy of Travoprost Ophthalmic Solution, 0.004% (preserved with POLYQUAD) is noninferior to Timolol Ophthalmic Solution (0.5% or 0.25%) in pediatric glaucoma patients.
The documentation of safety and performance of silicone oil as temporary tamponade in retinal surgery.
Primary: to evaluate the effectiveness of two treatment regimens by assessing the average stable maximum best-corrected (BCVA) change from Month 4 to Month 12 compared to Month 3. A treatment regimen will be considered a relevant treatment option if…
Primary Objective: Detect a difference in immunological profile between primary Sjögren*s syndrome patients in comparison with subjects from the other study groups.Secondary Objective(s): Other objectives will be the assessment tear osmolarity in…
The aim of this study is to investigate whether skin autofluorescence (AF) is predictive of postoperative PVR (and corresponding surgical failure) in patients being surgically treated for retinal detachment and to investigate some pathways which may…
The primary study objective is to assess whether TCS in cataract patients is a predictor of postoperative VA and if so, whether it is a better predictor than currently routinely used measurements, as represented by preoperative VA measurement…
We aim to investigate whether a relation between intestinal microbiota composition, mucosal integrity and translocation of bacteria into adipose tissue of the affected eye is related to the severity of Graves orbitopathy.
Development and validation of the D-AI KIDS and the D-AI YA:Currently there is no standardized instrument that measures visually impaired children*s and young adults' participation based on the nine ICF-CY domains. The primary objective of this…
Development of a method and diagnostic instrumentation for characterizing the peripheral ocular characteristics of normal subjects (with healthy eyes) in a clinical setting.Primary objective of the study: To measure the distribution of the ocular…