23 results
Primary objectiveTo evaluate the effects of treatment with MyopiaX on the rate of myopia progression in children and adolescents as reflected in spherical equivalent refraction and axial length changes at 6months relative to baseline.Secondary…
This study will evaluate the effectiveness and safety of a 36-week refill regimen for the PDS with ranibizumab 100 mg/mL (PDS Q36W) compared with intravitreal injections of aflibercept (2 mg) administered per a treat-and-extend regimen (aflibercept…
To evaluate the safety of EndoArt® in subjects with chronic corneal edema.
Primary: to determine the loss of corneal endothelial cells after implantation of a Paul GDD with its tube either anterior or posterior of the iris. Secondary: to compare efficacy and safety of both procedures.
The goal of this study is to characterize the natural history of STGD1 patients with the appropriate genotype for AON therapy and to identify the best clinical outcomes to measure therapeutic efficacy in clinical trials following completion of this…
Our study objective is to evaluate the efficacy of acetazolamide for the treatment of cystoid macula edema in inherited retinal dystrophies in anticipation of future clinical trials.
Our study objective is to investigate the reliability of commonly used clinical examinations and endpoints performed in patients with inherited retinal dystrophies in anticipation of future clinical trials.
Connection Interrupted: Genetic causes and clinical characteristics of hereditary optic neuropathies
The goal of this study is to identify the genetic causes underlying hereditary optic neuropathies and establish genotype-phenotype correlations. This will lead to more reliable prognosis predictions, better genetic counselling and hopefully form a…
This study has been transitioned to CTIS with ID 2024-516379-34-00 check the CTIS register for the current data. Objectives:To compare the efficacy of Atropine 0.05% to Atropine 0.5% treatment in European children with progressive myopia, and to…
The objective of this study is to determine which problems arise from different levels of impairments in visual and auditory functions. We will especially focus on the areas of access to information, communication, fatigue and mobility.
The primary objective of this study is to compare the binocular uncorrected intermediate visual acuity (UIVA) at 66 cm under photopic conditions 3 months postoperatively, in a series of patients bilaterally implanted with the Acunex® Vario IOL…
The overall objectives of the study are to evaluate the long-term safety and durability of GT005 in participants with GA secondary to AMD who have been treated in an antecedent study.
To detemine whether the Paul tube induces less damage to the corneal endothelium than the Baerveldt GDD.
To determine the safety and feasibility of fluorescence imaging of the eye vascularization with the fluorescent tracer bevacizumab-800CW for identification of neovascular Age-related Macular Degeneration (AMD) with scanning laser angiography.
Primary • To evaluate the efficacy of QR-421aSecondary• To evaluate the safety and tolerability of QR-421a • To evaluate changes in Patient-Reported Outcome (PRO) measures in subjects treated with QR-421a• To evaluate systemic exposure of QR-421a
The aim of this study is to get more insight in the pathogenesis of (P)SCR by comparing: (1) Red cell characteristics (deformability and point of sickling in hypoxia measured by the Oxygenscan), (2) Angiogenesis by determining several biomarkers of…
Cost-utility and cost-effectiveness of eye-screening in home healthcare in reducing eye complaints from a societal perspective and its health consequences will be investigated over 1 year. A cluster randomized controlled trial (RCT), including an…
Diabetic Macular Ischemia (DMI) is a complication of diabetic retinopathy (DR) and can lead to vision loss. Currently, there are no approved or effective treatments to prevent either onset or progression of DMI in DR patients.As a transition from…
The VAT project is set out to prove that this approach is superior and that the Quality of Life of children with amblyopia might be significantly improved in comparison to occlusion therapy.
This study has been transitioned to CTIS with ID 2024-511575-15-00 check the CTIS register for the current data. The main objective is the measure the effect on subretinal and intraretinal fluid in severe cCSC calculated by the cumulative areas of…