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Identifying progression of retinal disease in eyes with NPDR in diabetes type 2 using non-invasive procedures.

To identify eyes that show worsening and disease progression (progressor phenotypes). Primary ObjectiveTo identify *progressors* in retinal vascular disease and central retinal edema in type 2 diabetic patients with early NPDR, based on retinal…

Comparison of the Optos 200Tx non-mydriatic fundus camera and the Topcon TRC-50DX camera for
diabetic retinopathy evaluation

Primary Objective: To compare the quality of fundus photographs taken by (1) the Optoscamera in miosis and (2) the current camera in mydriasis.Secondary Objective: To compare the quality of fundus photographs taken by (1) the Optoscamera in miosis…

Phase-resolved Optical Coherence Tomography study.

A comparison of the PR-OCT and conventional ways of examination of patients, being slitlamp biomicrsocopy combined with stand alone SD-OCT, and fluorescein / ICG angiography, or glaucoma screening.

Near-Infrared Fluorescence Molecular Imaging of ANXV-800CW to Visualize its Biodistribution in the Eyes of Patients Suffering from Retinal Vein Occlusion and Diabetic Retinopathy

The primary objectives1. To assess the safety and tolerability of intravenous tracer administration of ANXV-800CW in up to three doses (0.5 mg, 1.0 mg, 2.0 mg flat dose) in patients with RVO and/or DR2. To determine the feasibility of molecular…

A First in Human trial to study safety and tolerability of single rising intravitreal doses (oPen label, non-randomized, uncontrolled) and in Addition the early biological Response of mulTiple intravitreal doses (double-masked, RandomIzed, shamcontrolleD) of BI 765128 in panretinal photocoaGulation (PRP) treated diabetic rEtinopathy (DR) patients with diabetic macular ischemia (DMI) - the PARTRIDGE Study

Diabetic Macular Ischemia (DMI) is a complication of diabetic retinopathy (DR) and can lead to vision loss. Currently, there are no approved or effective treatments to prevent either onset or progression of DMI in DR patients.As a transition from…