8 results
To investigate whether peak melatonin level and daily secretion patterns differ between delirious and non-delirious older persons admitted to the ICU. To determine factors that potentially influence the association between delirium and melatonin…
The overall objective of this study is to identify valid biomarkers for POD/POCD.
To assess in vivo microglial activation (as a validated marker of neuroinflammation) using PET-CT and associated neuropsychological characteristics in patients recovered from sepsis associated delirium.
To study the relationship between (a) abnormal concentrations of plasma amino-acids, pterins, HVA and inflammatory parameters and (b) the severity, duration and outcome of delirium. To find a biochemical profile that predicts the occurrence of a…
The main aims of the proposed study were (1) to determine the effect of delirium on cognitive-, psychological-, functional-, and health outcomes at discharge, 3, 6 and 12 month follow-up. Patients with a delirium at admission will be compared with…
Primary questions: 1) Is there a significant difference between the postoperative levels of 6-sulfatoxymelatonin (6-SMT, metabolite of melatonine) in 24 hour urine samples, in elderly patients with traumatic hip fractures, with and without a…
To compare the effects of a preoperative PA program in addition to usual care versus usual care only on the change in SB from baseline (T0) to the end of the preoperative (intervention) period (T1) in patients with TAD.
Detection of delirium superimposed on pre-existing cognitive impairment or clinically manifest dementia (DSCID) is extremely challenging. As a direct consequence of these diagnostic difficulties patients tend to be misdiagnosed and thus mistreated.…