58 results
The main objective of this study is to compare levels of stress reactivity, social anxiety and cortisol in daily life between adults with ASD and healthy controls. Besides, fluctuations and interactions of these variables over time and their…
1. To identify genetic variants associated with an increased risk of ASD using different genetic models (dominant, recessive, interaction).2. To determine the relationship between different genetic variants and the associated neuropsychiatric ASD…
The primary objective of the proposed study is to investigate whether bumetanide therapy indeed reduces autistic symptomatology. Important secondary goals of this project are to determine whether bumetanide will improve specific behavioral,…
To study sensory processing and hyperexcitability in children with ASD and epilepsy using neurophysiological measurements (EEG/ERP).
To assess in paediatric patients with ASD with and without (first-time) antipsychotic medication• the prevalence and incidence of insulin resistance and other metabolic abnormalities• the risk factors for insulin resistance and other metabolic…
In this study we use a unique paradigm which can be used to examine both high-level (serial dependence) effects as low-level (adaptation) effects. By doing so we hope to resolve the discrepancy in the previous findings. We expect that low-level…
The main objective of the current study is to examine whether people with ASD have over-active inhibitory inter-connections in visual processing areas that can account for their over-sensitivity to perceptual dissimilarities.
The objective of this study is to know more about the relationship between cognitive copingstrategies and anxiety and depression. This knowledge is helpfull in development of treatment for anxiety and depression in ASD.
We aim to identify biomarkers (from neuroimaging, eye tracking, EEG, cognition, biochemistry, proteomics, genomics) for stratification of ASD. Biomarkers will be crucial to aid more accurate and earlier diagnosis of ASD. They are also needed for…
Our primary objective is to investigate the development of structural and functional connectivity in autism and ADHD in comparison to the typical development of connectivity. A secondary objective is to investigate the effects of ADHD and autism…
This study has two main objectives. One objective is to investigate which cognitive and affective mechanisms can be influenced through treatment which leads to improved social functioning. We will use a carefully selected set of behavioral,…
The main aim of the current study is to specify neurocognitive mechanisms behind rigid behaviour in autism. For this reason, participants will be required to execute a computer task, in which they will need to make their own choice of tasks, during…
The purpose of this study is to test whether perceptual expectations modulate V1 activity consistent with *hypo-priors* in autistic individuals.
This study aims to gain more insight in the sexual development of adolescent boys with ASDs.The main research question is: How do high functioning boys with ASD develop sexually? The main research question is worked out in 2 parts/1. Which sexual…
The main objective of this study is to determine how children with ADHD and ASD differ from each other in learning from social and material reward. The secondary objectives are: 1) To determine how predictability of the rewards influences learning…
This study has two main objectives. The first objective is to investigate whether children with DBD, when compared to low aggressive and antisocial control children, have neuropsychological and neurobiological abnormalities that may underlie their…
We intend to study the role of fronto-striatal circuitry and cognitive control in the inflexible behaviour that is a defining feature of autism.
Examine whether there are differences in both instrumental as well as clinical assessment of movement disorders among drug naive patients with autism compared with matched healthy controls.
The present study has the following objectives:1) Investigating the clinical utility of screening instruments. As a part of this objective, we will examine how several demographics (e.g. ethnicity) affect the assessment of autistic and other…
Objective: Our general objective is to investigate the neurobiological substrates of a broader ADHD phenotype.