21 results
Empathy is related to quality of life, depression, insight and social functioning and may be an important factor in recovery of people with schizophrenia. Empathy is impaired in schizophrenia, however it is not clear which elements of empathy are…
The main goal of the study is to develop and validate a device that provides an objective measure of degradation of motor performance in elderly people. The device will assist to diagnose neurodegenerative disorders in the elderly at an early stage…
The goal of the present study is to gain understanding of the brain mechanisms underlying the impairment of multisensory integration processes in schizophrenia. The study will support the development of more precise criteria for the diagnosis of…
To establish the validity of the self-report version of the AVHRS-I interview, the AVHRS-Q.
to assess whether a single-dose of levodopa improves cognitive symptoms and balances goal-directed and habitual behavior.
The main goal of our proposal is to study the interaction between cognitive and emotional capacities in schizophrenia. In numerous studies patients with schizophrenia show impairments in all major cognitive domains (6) as well as impairments in the…
The aim of the present study is to investigate the semantic network of patients with psychosis with current auditive hallucinations, patients with psychosis without current auditive hallucinations, first degree relatives of patients with psychosis…
The general purpose of the present study is to test whether people with schizophrenia perform differently when assessing working-memory tasks measuring different components. A better knowledge of working memory impaiment in schizophrenia could lead…
The aim of the present study is to investigate the neural correlates of the semantic network of patients with recent non-affective psychosis, first degree relatives of patients with psychosis and healthy controls. Furthermore, the relationship…
P.11: This study seeks to contribute to our understanding of factors which contribute to violence in persons diagnosed with psychotic disorders, in order to improve clinical risk assessment and guide treatment choices.
Primary Objective: The aim of this study is to determine a cut-off score at the PQ-16 with the CAARMS for better detection of adolescents 12-18 years at risk. Secondary Objective(s): To study the course of UHR in adolescents 12-18 years over a one…
The main objective is to measure activity levels using an accelerometer in healthy participants, patients with schizophrenia scoring low or average on apathy (< 27 on the apathy items of the Apathy Evaluation Scale (clinician rated; AES-C),…
The objective of the study is to identify the phenomenological differences and similarities in characteristics of voices between patients with a dissociative identity disorder and patients with a schizophrenia spectrum disorder with and without a…
1. To assess whether a. Neuromelanin-sensitive MRI (nMRI) is a suitable biomarker for TRb. Plasma DDC activity is a suitable biomarker for TR2. To increase our insight in the role of glutamate in the anterior cingulate cortex (ACC) in TR and assess…
The primary aim of this research is to test the psychometric qualities of the Dutch translation of the CAI-NL. The secondary aim of the study is to evaluate the clinical value of the CAI-NL as an instrument in the treatment of people with severe…
Translating neuroimaging findings from research into clinical practice (PSYSCAN):
Clinical High Risk
Primary objective of the current study is to develop and validate a prediction tool focusing on illness onset, course and outcome at an individual level in individuals at high risk for developing psychosis. This will be achieved by combining the…
Primary objective of the current study is to develop and validate a prediction tool focusing on illness course and outcome at an individual level after patients have experienced a first episode of psychosis. This will be achieved by combining the…
In the present study we are interested in the interaction between these two deficits in patients with schizophrenia using faces as visual objects. One of the important issues that will be addressed is that if the emotional content represented by the…
The goal of this study is to collect pilot data using the neuromelanin sensitive MRI sequence in patients with schizophrenia of psychoses, patients with Parkinson's disease and healthy controls. These pilot data will be used for grant…
1.1 Primary ObjectiveTo test the validity and reliability of two new VR emotion recognition tasks in people with psychotic disorder. This will be done by comparing the tasks to classical tests and to compare data of people with a psychotic disorder…