486 results
To quantify muscle relaxation properties of fingerflexors using transcranial magnetic stimulation in patients with different myopathies to develop a screening diagnostic tool to assess who does (not) suffer from an underlying myopathy.
The primary goals of this study are to: i. Identify genetic variations responsible for PLP across the whole genomeMore than 90% of SNPs are found in introns or intergenic regions and most of them are probably of little functional consequence.…
to determine the percentage of patients with CKD, without a history of gout or attacks of arthritis, that have tophi measured by US,DECT and clinical examination. to determine the percentage of patients with CKD, that have tophi measured by US, and…
To define the amount of dietary protein required to optimally stimulate post-exercise muscle protein synthesis in the older population.To assess whether co-ingesting 1.5 g of free leucine (contained within 15 g dairy protein) along with 15 g protein…
To Establish the usefulness of MRI for assessment of the rotator cuff in patients with an Affinis short prosthesis implanted in the shoulder.
Primary aim: Stepwise feasibility study to investigate whether intravenously administered macrophage tracers [11C]DPA-713, [18F]DPA-714 and/or [18F]PEG-folate accumulate in inflamed joints of rheumatoid arthritis patients using PET(-CT).Secondary…
The goal of the study is whether to establish if application of combined cyrocompression therapy directly postoperative after hip fracture surgery results in a significant reduction in painperception en whether this reduces the morfine consumption.…
Primary objective of this study is to assess the feasibility of using a monitoring and a titration algorithm to prevent inactivity and excessive activity of the diaphragm. This will be determined by comparing the fraction of breaths where diaphragm…
The overall objective is to investigate the efficacy of resveratrol in modulating metabolism and CVD risk profile in patients with COPD. The primary objective is to investigate the effect of resveratrol on CRP as clinical marker of low grade…
To conduct a randomised controlled trial to determine differences in outcomes of the TT and AMP ACL reconstruction techniques by means of MRI signal SI of the ACL graft. Secondly, differences in clinical, functional and patient-oriented outcomes of…
To examine the effectiveness of an unsupervised e-health supported neuromuscular training program in combination with usual care in general practice compared to usual care alone in patients with acute lateral ankle sprains in general practice.
The main objective is to identify objective, neuromuscular and/or mechanic parameters through movement analysis, which are closely correlated to the subjective outcome of TKA. Secondary objective is to generate parameter specific hypotheses for our…
The main objective of this study is to assess the prevalence cardiovascular disease and the prevalence of risk factors for cardiovascular disease in patients with gout, and to quantify the risk for cardiovascular disease in patients with gout. The…
The aim of this exploratory study is to compare the hemodynamic response as determined by the HandScan between patients with OA and RA, and to study these hemodynamic responses in relation to disease specific underlying joint pathology (synovial…
The aim of this study is to evaluate the quality of the cartilage of repaired defects 20-25 years after perichondrium transplantation (PT) or autologous chondrocyte translantation (ACT). Secondary objectives are to review the functionality and pain…
To evaluate the role of white blood cell (WBC) scintigraphy in monitoring the response of infection treatment of a prosthetic joint infection.
Primary objective of this study is to assess the reliability, validity, and diagnostic value of the neuromechanical parameters of joint impedance estimated by nonlinear SIPE technology in patients with a spastic paresis.
1. To explore the validity and usefulness of Bone Microindentation Technique (BMT) in the assessment of bone quality in patients with osteoporosis and a spectre of bone diseases characterised with (localised) increased bone turnover. 2. To study the…
1. The primary objective is to evaluate the characteristics of the distal radial growth plate on MRI (including functional imaging techniques) and on conventional radiographs in young gymnasts with wrist pain, compared to young gymnasts without…
The primaire objective is to evaluate the effectiveness of a multicomponent intervention (MCI) programme (physical activity [PA], nutritional counselling/dietary intervention, and information & communication technology [ICT] intervention)…