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Trans rectus sheath preperitoneal mesh repair (TREPP) versus transinguinal preperitoneal procedure (TIPP) for inguinal hernia repair: a multi-center randomized controlled trial.

Reduce postoperative chronic pain after open inguinal hernia repair.

A prospective clinical study on the efficacy of collagenase clostridium histolyticum (CCH) injections in the thumb and first web space contractures in Dupuytren*s Disease

To evaluate the effectiveness of CCH as treatment for Dupuytren*s contracture in the thumb and first web space by assessing pre- and post treatment extension deficit and adduction contracture.

Effects of bosentan in a homogeneous population of SSc subjects with an early or active SSc nailfold capillaroscopic pattern

Primairy objective:- Evaluate the effect of bosentan on the blood flow in the hands from baseline to 12 weeks, measured by laser Doppler imaging, in SSc subjects with an early or active SSc pattern, measured with nailfold capillaroscopy (NFM), with…

Natural disease progress of Dupuytren's disease

The primary aim of this study is to gain knowledge on the natural course of Dupuytren's disease, in adults with various Dupuytren disease stages. Secondary aims are: - Gain insight in course after treatment- Determine whether there are risk…