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Prospective Hounsfield Unit measurements of intercorporal bone grafts remodelling towards spinal fusion.

This study has three specific objectives:1) to explore how the participants* intercorporal bone grafts HU develop over time in the first two years after fusion surgery.2) to explore the interobserver reliability of the HU measurements.3) to explore…

Phase 3 Randomized, Placebo-Controlled Study to Assess Safety, Tolerability, and Efficacy of Garetosmab in Patients with Fibrodysplasia Ossificans Progressiva

This study has been transitioned to CTIS with ID 2023-508350-26-00 check the CTIS register for the current data. Primary ObjectiveThe primary efficacy objective of the study is to assess the effect of garetosmab (10 mg/kg) versus placebo on the…

A Randomized, Blinded, Placebo-controlled, Phase 2 Study of INBRX-109 in Unresectable or Metastatic Conventional Chondrosarcoma

This study has been transitioned to CTIS with ID 2024-517528-20-00 check the CTIS register for the current data. Primary objective:• To evaluate the anticancer efficacy of INBRX-109 in the intention-to-treat (ITT) population as measured by…