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Does extracorporal shockwave therapy result in short term improvement of
tendon structure in symptomatic midportion Achilles tendinopathy?
An ultrasound tissue characterisation study

This research is part of the evaluation of regular care.Primary objective:(1) to investigate whether 4 weekly shockwave treatments for soldiers with mid-portion Achilles tendon endopathy result in an improvement in Achilles tendon structure after 8…

Individually optimised rocker profiles to reduce mechanical load in patients with Achilles Tendinopathy and Plantar Fasciitis.

The objective of this study is to evaluate the biomechanical effect of the newly developed rocker soles aiming to reduce the mechanical load in patients suffering with Achilles tendinopathy and plantar fasciitis. A secondary objective is to evaluate…

Cost-effectiveness of biceps tenotomy with or without cuff repair in patients
with stage 2-3 Goutallier fatty degenerative cuff lesions. A randomized
controlled multicenter trial.

this multicentre randomized controlled non-inferiority trial is designed to compare the short and long term outcome of patients who underwent an arthroscopic tenotomy of the long head of the biceps tendon with or without a cuff repair.

Study Protocol Title: A Prospective, Open-Label, Multicenter Pivotal Study to Evaluate the Safety and Efficacy of GelrinC® for the Treatment of Symptomatic Articular Cartilage Defects of the Femoral Condyle: A Comparison to Historical Control Microfracture

To demonstrate the superior clinical efficacy of GelrinC on pain and function for the treatment of symptomatic focal articular cartilage defects of the femoral condyle in comparison to microfracture historical control at 24 months post-surgery.

Dynamic Intraligamentairy Stabilisation of the acute torn anterior cruciate ligament, a multicenter prospective cohort study.

To assess the efficacy of treatment of acute ACL ruptures with the Ligamys device.

Validating the Positioning Protocol for Whole Leg Radiography

Primary Objective: Test-retest reliability of the measured HKA when patients are positioned following our specific positioning protocol.The main study parameter will be measured using the method as in the current practice. This is a manual method,…

comparison between different types of gastrocnemius-soleus stretching in the treatment of plantar fasciitis: posterior night splint, soft night splint of a custom-made cast.

To assess the clinical outcome and evaluate the effectiveness after treatment of plantar fasciitis with a posterior tension night splint (Pro Orthics), soft night splint (Strassbourg sock) or custom made cast for the treatment of plantar fasciitis…

The effect of coblation treatment on knee cartilage quality in patients with meniscal lesions and cartilage loosening of the knee

Primary Objective: To study the in vivo effect of coblation treatment on knee cartilage quality in patients with meniscal lesions and partial cartilage loosening of the knee.Secondary Objective: To study the relationship between knee cartilage…

Effect of neurocognitive load during hop tests on jump distance, muscle activity and joint angles in patients with anterior cruciate ligament (ACL) reconstruction versus healthy individuals

To investigate the hypothesis that both patients with an ACLr and individuals without a knee injury show a significantly reduced jump distance during hoptests with a neurocognitive load compared to traditional hop tests.

Surgery and exercise versus exercise only for chronic patellofemoral pain syndrome: a randomised controlled trial.

Zie het onderzoeksprotocol 2: "Objectives".

Intraoperative arthroscopic near-infrared fluorescence imaging of the vascular perfusion of the meniscus in patients treated with meniscal repair

To investigate the possibility of NIR fluorescence intra-operative angiography of the meniscus using ICG in patients undergoing arthroscopic meniscal repair.

A multi-center, pivotal, non-randomized, prospective, open-label study to evaluate the safety and performance of the Hy2Care Injectable Hydrogel for the repair of cartilage defects in the knee.

Primary objectives:Safety:To demonstrate the safety of the investigational device in 10 subjects at 3 months post-surgery.Safety cohort data will be pooled with the performance cohort data, to measure the performance and safety of the…

Exploring underlying mechanisms of paediatric growth disorders using human ex vivo growth plates.

The current study is designed to collect viable growth plate tissue of tall statured individuals that undergo percutaneous epiphysiodesis (PE). With this collected biomaterial we will be able to characterize dynamic changes in growth plate…

Prospective Hamstring Avulsion Registry for Outcome following Surgical and nonoperative treatment

The main goal of PHAROS is to systematically gather prospective clinical data on full-thickness hamstring injury due to tendon avulsion or rupture in order to gain insight into clinically relevant outcomes, to identificate prognostic factors and to…

Dynamic Computed Tomography for assessment of Knee Rotational Stability after Anterior Cruciate Ligament Injury

For this technique is new and has never been applied for assessment of knee stability, our first goal is to assess the normal rotational stability of the compared to the ACL­injured knee. Measuring knee rotational stability of ACL deficient compared…

Randomized controlled trial on clinical outcomes and safety of Instant MSC Product accompanying Autologous Chondron Transplantation (IMPACT) for focal articular cartilage lesions of the knee

This study has been transitioned to CTIS with ID 2024-514612-27-01 check the CTIS register for the current data. The primary objective is to measure the level of clinical improvement and quality of life at 3, 6 and 9 months compared to…

*A prospective randomized multicenter study to demonstrate the superiority of the Barricaid® to discectomy for primary lumbar disc herniation*: Extended Follow-Up of the Barricaid® Annular Closure Device (ACD) Randomized Control Trial (RCT) Postmarket Cohort for Lumbar Disc Herniation and Interaction with Other Risk Factors

The purpose of this post-approval protocol amendment is to extend the follow-up of subjects who were originally enrolled in theRCT, EUBARD-CP_001 protocol. This study extension will examine the long-term survivorship of the Barricaid® ACD when…

Diagnostic performance of dynamic four-dimensional computed tomography (4D CT) for analyzing wrist ligament injuries - a reproducibility study of the image acquisition protocol.

The study wants to investigate the intra-patient test-retest reliability to show the robustness of the acquisition protocol to contribute to the standardization of a 4D CT wrist image acquisition protocol, with the use of a forearm fixation device…

Lateral ligament repair for ankle instability protected with internal bracing. A multicenter, randomized controlled trial.

To evaluate if patients with chronic, recurrent lateral ankle instability who are treated with surgical lateral ankle ligament repair protected with an internal brace, have significant better ankle function after surgery compared to patients treated…

Single-handed, double loaded: The effect of an increase in biomechanical loads and central sensitization on the presence of musculoskeletal complaints in upper limb absence and brachial plexus injury.

The overarching aim of this project is to study the factors contributing to MSC in individuals with one functional hand. The two primary objectives are: (P1) to examine the presence of muscle fatigue, caused by imbalance between biomechanical loads…