14 results
To evaluate the effects of intravenous iron suppletion in iron deficient PAH patients.Amendment: to compare exercise capacity and isolated muscle strength in IPAH patients and healthy controls
PRIMARY OBJECTIVE1. To determine the contractile strength and the (ultra)structure of single diaphragm muscle fibers of mechanically ventilated patientsSECONDARY OBJECTIVE1. To determine whether diaphragm muscle fiber weakness is part of a…
The purpose of GRN-study is: 1. to determine the long-term effectiveness of a 12 weeks lasting physical exercise training program. 2. to determine the costeffectiveness of the 12 weeks lasting physical exercise training program. In aim of the GRN-…
The aim of this study is to assess the effect of training on the measurement properties of a recently developed disease activity score based on patient reported outcomes and to investigate if such a measure could be implemented in current clinical…
The primary objective is to determine whether the diaphragm develops contractile fatigue during a weaning trial and if this is associated with weaning failure. Furthermore, the hypothesis whether diaphragm efficiency (Effdi = electrical activity of…
In this study we want to investigate if relaxation time (RT) measured by handgrip myometry and muscle- elastography is a reliable outcome measurement for the quantification of myotonia in NDM patients. Mean RT values en standard deviations of NDM…
The objective of this pilot study is to demonstrate that NAVA ventilation is superior compared to pressure support and pressure control ventilation in work of breathing (expressed as pressure-time product) patient ventilator synchrony and other…
The primary aim of this study is to identify the muscles that are most critical to the abnormal standing posture, standing balance and gait in FSHD patients and to elucidate the most important mechanisms of falls. The ultimate goals are (1) to…
To investigate the relationship between self-reported disability, performance based disability and psychological factors in patients with complaints of whiplash.
The objective of this study is to determine whether the intake of protein with extra leucine or extra carbohydrates added results in an improved muscle protein synthesis compared to the intake of only protein in elderly.
To investigate the effects of three different methods of finding a suitable recording site for CMAP and three different electrode sizes on CMAP amplitude and its reproducibility
The objective of the studie is to develop a reliable and discriminative measurment protocol to determine the upper extremity function in boys with DMD. This measurement protocol will be based on 3D movement analysis and surface EMG measurements.
The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.
The aim of the represent proposal is twofold, 1. [PHASE 1] the establishment of a human tissue biobank including muscle and blood, and additionally from a subset subset of subjects fat and skin biopsies will be taken. Samples will be distributed…