26 results
To quantify muscle relaxation properties of fingerflexors using transcranial magnetic stimulation in patients with different myopathies to develop a screening diagnostic tool to assess who does (not) suffer from an underlying myopathy.
The primary objective of this study is to compare respiratory muscle strength values obtained using volitional techniques with values obtained using non-volitional techniques. The secondary objective is to compare the change for these two sets of…
In this project we use skeletal muscle biopsy tissue from DM1 patients and controls to isolate pericytes. These muscle-derived mesodermal cells can be genetically corrected by the novel powerful CRISPR-Cas9 technique, which will remove the disease…
Primary objective:Effect of fecal transplantation (from healthy obese donors) on faecel microbiota composition in relation to satiety (questionnaires, biomarkers) and metabolism (REE ) in patients with metastasized or locally advanced oesophageal or…
The aim of this study is to conduct a pilot study of weight-supported ambulation training in ICU patients and to assess its feasibility of the use in daily practice, and to obtain information for the development of a randomized clinical trial for…
To investigate the acceptability and feasibility of exercise therapy in an aquatic environment by patients after burn injury.
The primaire objective is to evaluate the effectiveness of a multicomponent intervention (MCI) programme (physical activity [PA], nutritional counselling/dietary intervention, and information & communication technology [ICT] intervention)…
First we want to determine whether early high protein intake, using an enteral whey protein supplement, in addition to a standardized exercise training program and standard enteral nutrition preserves: a) in vitro skeletal muscle function in…
The primary objectives of this study are (a) to evaluate reliability and precision of an instrumented spasticity assessment device (ISA) in children with cerebral palsy and adults with spastic paresis (MS and stroke patients) and (b) to validate ISA…
To obtain some control values for the MRI biomarkers for fatty infiltration and edema-like lesions in skeletal muscles of healthy volunteers.
Using technology for improving diagnostics of non-specific lower back pain by physiotherapists
The primary objectives of this project are to assess the mtDNA mutation load in carriers of a mtDNA mutation and identify patients and/or mutations with with no/low mtDNA mutation load in mesoangioblasts. Secondary objectives aim at determining the…
To provide evidence for the efficacy of Branched Chain Keto Acids (BCKA) and Branched Chain Amino Acids (BCAA) when compared with milk proteins to stimulate postprandial muscle protein synthesis in vivo in healthy older humans.
This study examines the feasibility and an indication of possible effects of ZORA robot based intervention on play in rehabilitation and special education for children with severe physical disabilities.
This study aims to investigate the impact of a newly developed oral nutritional supplementation (ONS_01) primary on body weight and lean body mass and secondary on physical performance, muscle health and immune function in malnourished elderly…
- To assess the reproducibility of the LET.- To define the relation between the LET and clinical severity in HypoPP patients.
We aim at investigating the role played by the innate and adaptive immune system and orienting a proper treatment. We will evaluate the percentage and features of circulating activated immune cells and cytokine production. As a second step, we will…
Primary Objective: To determine if spinal and cortical balance control mechanisms mediate the age-associated decline in balance skills. Secondary Objective: To determine the reliability of TMS and H-reflex measures in the soleus muscle in different…
Primary:* To assess the efficacy of idebenone compared to placebo, in delaying the loss of respiratory function in patients with DMD receiving glucocorticoid steroids as measured by changes in Forced Vital Capacity percent predicted (FVC %p) using…
The primary aim is to study if systemic or cerebral reactivity in DMD patients differs from healthy age-matched controls, to determine whether 1) cerebral autoregulation or 2) systemic blood pressure underlies the reduced cerebral perfusion in DMD.…