12 results
Primary Objective:1) To determine the efficacy of personalized progressive resistance training (PRT) on muscle strength of elbow flexors in children and adolescents with Spinal Muscular Atrophy and Congenital Myopathy compared to usual care…
To compare the effectiveness of a diet with beef as key protein source versus an isocaloric and isonitrogenous plant-based diet to stimulate integrated muscle protein synthesis rates over a 10 day period, in healthy older individuals, with and…
Primary objective• To characterise natural disease progression rates of MRI- and/or US-assessed measures of muscle properties and muscle function and strength tests in children with neuromuscular disorders through standardized annual follow-up…
To assess the effectiveness of daily protein supplementation with either a plant based protein blend or a milk protein on top of a standard diet to stimulate integrated muscle protein synthesis rates in healthy older individuals with and without…
To assess the impact of short-term forearm immobilization on forearm muscle glucose uptake and amino acid net balance and kinetics of individuals with T2D compared with a control group with normoglycaemia.
To examine the effect of a single session of whole-body NMES, with or without subsequent protein intake, on whole-body protein turnover
In this clinical project we aim to fill in gaps in our knowledge on muscle fiber contractility, auto-immunity and myositis: 1) How responsive is human muscle fiber contractility following standard of care immunosuppressive treatment? 2) Is the…
The primary goal of this study is to identify immunological alterations in blood, lymphoid tissue, bone marrow and muscle in IIM patients. Furthermore, our objective is to specifically profile autoreactive B lineage cells from IIM patients isolated…
To answer the following questions; (1) What is the estimated effect size of personalized rehabilitation therapy for improving daily functioning in severely fatigued myositis patients, compared to usual care? (2) What are the societal costs of…
Primary objective: To quantify the degree of respiratory muscle degeneration and dysfunction using ultrasound in patients with DMD over a wide age range; from early childhood to adults.Secondary objective: To determine the association between…
Primary Objective: to investigate the prevalence of bruxism and TMD in PD patients through objective measurements.Secondary Objectives: to identify factors associated with the presence of TMD or bruxism in a PD population.
Primary Objective: Development of an DTI sequence for muscle fibre integrity assessment of the swallowing musclesSecondary Objective(s): 1. Reproducibility assessment of the muscle fibre integrity assessment with DTI in healthy volunteers: (a)…