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Favorable and unfavorable effects of risk-reducing salpingo-oophorectomy (RRSO) in women at high genetic risk of ovarian cancer

Primary Objective: To study long-term effects of premenopausal risk-reducing salpingo-oophorectomy (RRSO) on - cardiovascular status- bone mineral density- cognitionSecondary Objective: To study long-term effects of premenopausal RRSO on - quality…

Cost-effectiveness of perioperative vaginally administered oestrogen in postmenopausal women undergoing prolapse surgery.

Primary Objective: This study aims to comprehensively compare the effectiveness and costs of perioperative topical oestrogen for postmenopausal women undergoing POP surgery. In this trial, the perioperative use of oestrogen is considered superior to…