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Markers for neurocognitive impairment in congenitally CMV infected infants: MARVELYS study

1. To characterize long-term neurologic- and cognitive disorders, audiological and ophthalmological alterations in cCMV-infected children.2. To identify immunological, neurological host factors and virological factors that are predictive of…

A randomized, open-label, two-way crossover study to assess the relative bioavailability of Laquinimod 0.6 mg test tablet versus Laquinimod 0.6 mg reference capsule after single dose administration with a single sequence extension to assess the pharmacokinetics of Laquinimod and its metabolites after single and multiple oral 0.6 mg dose administration in healthy subjects.

The study will be performed in 2 parts, Parts 1 and 2. In Part 1, single doses of laquinimod will be administered whereas in Part 2, multiple doses of laquinimod will be administered. The study will be performed in a maximum of 20 healthy male and…

Neurological, visual and neurocognitive performance in perinatally HIV-1- infected patients as compared to healthy controls.*
NOVICE II Follow up study

To increase insight in cerebral injury of perinatally HIV-infected children by comparing neurological, ophtalmological and neurocognitive outcomes to those of matched controls (with respect to age, sex, ethnic background, home environment and socio-…