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Walking-induced motor fatigability in Multiple Sclerosis: a pilot study on underlying mechanisms and the feasibility of sequential resistance and walking-specific endurance training

a) To study the relationship between ankle push off and walking-induced motor fatigability and the potential confounders of this relationship in persons with progressive MS and healthy controls. b) To assess the feasibility of a targeted, sequential…

BETAEVAL GLOBAL- The new BETACONNECT auto-injector: Adherence and EVALuation of MS patients treated with Betaferon®

To better understand the utilities of the new BETACONNECT device and characterize its contribution to adherence, we plan to prospectively follow-up MS patients using the device for 24 weeks.

A Phase 1 Randomized, Placebo-Controlled, Double-Blind, First- Time-in-Humans, Single-Ascending Dose (SAD) and Multiple- Ascending Dose (MAD) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CNM-Au8 in Healthy Male and Female Volunteers

Primary objective:To evaluate the single- and multiple-dose safety and pharmacokinetics of CNM-Au8 upon oral administration of CNM-Au8 to healthy adult male and female subjects.Secondary objective:Exploreing the immune-modulating effects of CNM-Au8…

A randomized, double-blind, placebo-controlled, cross-over study to assess the effects of fampridine on eye movements and nerve conduction and function in patients with multiple sclerosis (MS) and a unilateral or bilateral internuclear ophthalmoplegia (INO)

Primary objective: - to evaluate the effects of fampridine on eye movements in MS patients with a unilateral or bilateral INO. Secondary objectives:- to determine whether there is an association between MRI signal of the medial longitudinal…

Dance for Health: The effect of a dance program on patients with Multiple Sclerosis

The aim of the current pilotstudy is to investigate the effect of a standardized dance program (provided by the foundation Dance for Health) in MS patients. We will specifically investigate the effect of the dance program on the hippocampus and (…