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The use of direct nerve visualisation with the Evotouch/7starscope compared to the conventional fluoroscopy technique for transforaminal epidural injection.

We hypothesize that using the Evotouch/7stascope, ultrasound guided TFEI procedures are non-inferior to the golden standard with fluoroscopy, which means correct placement of the needle within the neuroforamen without intravascular positioning.

Efficacy of the Myosuit for increasing daily life gait performance in the home and community setting and gait capacity in people with incomplete spinal cord injury

Part A:The primary objective is to test the efficacy of the Myosuit, a soft exosuit, for increasing daily life gait performance in the home and community setting in people with iSCI. Secondary, the efficacy of the Myosuit program on gait capacity…

A Randomised, Double-Blind, Placebo-Controlled, Single- and Multiple-, Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of VRG50635 and Food Effect in Healthy Volunteers (Phase 1a)

Part 1; Single ascending dose (main objective)• To investigate the safety and tolerability of single oral doses of VRG50635 in healthy adult subjectsPart 1; Single ascending dose (secondary objective)• To characterize the plasma and urine…

Pulmonary function and sleep related disorders during cervical admission of intrathecal baclofen in spinal cord injury; a safety study

This study has been transitioned to CTIS with ID 2023-508143-51-01 check the CTIS register for the current data. Objective: The primary aim of the study is to demonstrate that cervical administered ITB is a safe treatment of spasticity of the UE…

The effect of vibrotactile feedback on exoskeleton use in people with complete spinal cord injury

The aim of the study is to investigate the effect of vibrotactile feedback on exoskeleton use in people with complete spinal cord injury.

A Randomized, Placebo-Controlled, Double-blind, Single Ascending Dose, First in Human Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of QRL-101 in Healthy Participants.

In this study we will investigate how safe the new compound QRL-101 is and how well it is tolerated when it is used by healthy subjects. A single dose of the study compound will be given to each participant. We will also investigate how quickly and…

The role of the relative aerobic load of walking and walking behaviour after spinal cord injury

The primary aim is to determine whether the relative aerobic load of walking is a determinant of the amount of walking in daily life in people with a chronic spinal cord injury with a walking function. Secondary goals are to gain insight into other…

The effectiveness of the Wim Hof Method on the physical and mental health of people with a spinal cord injury

The primary objective of this trial is to assess the effects of WHM, involving breathing exercises, mindset (and cold exposure), on health-related quality of life in people with SCI. The secondary objectives are to assess the effects of WHM,…

State-of-the-art nuclear neuroimaging in failed back surgery syndrome: can we predict the outcome?

Primary Objective: The primary objective of this study is to map cerebral glucose metabolism of patients diagnosed with FBSS in an effort to elucidate imaging biomarkers that could predict the effectiveness of SCS treatment. Secondary Objectives:…

Transforaminal Epidural Steroid Injections for Acute Lumbosacral Radicular Syndrome without prior consultation with a neurologist or diagnostic imaging.

The aim of this study is to evaluate the pain improvement of patients with aLRS treated with TFESI, after straight referral from the GP to the pain specialist without diagnostic imaging and prior consulta-tion with a neurologist. Pain improvement…