11 results
To determine the relative bioavailability of pramipexole 4.5 mg tablets vs. 4.5 mg Sifrol in healthy subjects after up-titration.
To report on (the age-dependency of) the long-term effect(s) of chronic SSRI treatment during adolescence or adulthood on the outgrowth and function of the 5-HT system, using state-of-the-art Magnetic Resonance Imaging (MRI) techniques and other,…
The primary objectives are defined according to a hierarchical design: i) to tailor and apply multi-parametric, functional MRI techniques to identify cerebral abnormalities (cerebral biomarkers) in DM2 and MetS; ii) to investigate which cerebral…
The current study will focus on the effects of an intensive programme of exposure of prism adaptation (i.e. daily exposure during two weeks) and compare these to sham adaptation.
Primary objective: To create diagnostic and treatment tools for navigation ability in stroke patients, that can be used in clinical practice.Secondary objective: To increase knowledge about the cognitive structure and neuroanatomical correlates of…
The main objective of this study is to characterize the flow of information in the fronto-parietal network during the simulation of movements using intracranial EEG recordings. In the characterization we will pinpoint the neuronal (sub)regions of…
Addictive disorders affect a steady proportion of the population, and result in significant negative personal consequences (e.g. loss of jobs, psychosocial problems) and costs to society (absence from work due to hangover, treatment costs). GHB is…
The primary objective is to evaluate the presence of brain damage (defined by white matter lesions (WMLs) or cerebral atrophy or deviations at neuropsychological examination (NPE)) among adults with tetralogy of Fallot (TOF). The secondary objective…
Primary Objective: To examine which subregions of the hippocampal formation on 7 Tesla MRI are most affected in patients with early Alzheimer*s disease compared with older persons with normal cognition. Secondary Objectives:a) To explore risk…
Primary objective: to assess the safety and tolerability and pharmacokinetics of LND101001 administered as single and multiple doses; Secondary: to assess the effect of food and gender on pharmacokinetics.
To assess the impact of OH on cerebral perfusion and function in severe OH in AF (n=10) and healthy controls (n=10).