8 results
High-field (7T) MRI and genetic biomarkers for neurocognitive impairment in type 2 diabetes melltius
The primary objectives: 1. To tailor and apply high-field multi-parametric and functional MRI techniques to identify cerebral biomarkers in DM2 and MetS patients compared to control subjects.2. To examine a specific set of genetic hypotheses in DM2…
To study the acute effect of HD on global and regional CBF.
Primary Objective: • To demonstrate that changes in blood pressure and cerebral perfusion (induced with paced breathing and the Cold-pressor test) can be assessed in the MRI using the combination of NIBP and rapid ASL measurements. Secondary…
Primary objective of this study: To establish glycocalyx properties of temporal lobe epilepsy (TLE) patients. Secondary objectives of this study:- To establish differences in glycocalyx properties of glycocalyx between TLE patients and controls.- To…
We address two primary objectives: 1.) To determine whether (awake) surgery on patients with a brain tumor or epilepsy allows for HD-ECoG data collection of adequate quality to address research questions on brain function. In other words, we want to…
Primary objective of the study: 1. To report on the long-term effect modification by age of MPH treatment on the outgrowth of the DA system using state-of-the-art Magnetic Resonance Imaging (MRI) techniquesSecondary objectives:1. To report on the…
This proof-of-concept study aims to non-invasively detect amyloid-beta (Aβ)-plaques in the retina of AD patients using a Heidelberg Spectralis scanner with Curcumin as labeling fluorophore. The retinal Aβ-plaques will be related to currently used AD…
The primary objective is to study the relationship between DAI lesions on conventional MRI, clinical parameters and prognosis. As secondary objective is the additive value of more advanced MR Imaging in which white matter tracts are analysed (as…